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Drug Information For:


Ingredient Name:

PREDNISOLONE (pred-NISS-oh-lone)

Drug Manufacturer:


Common Uses:

This medicine is a corticosteroid used to treat severe allergies, arthritis, asthma, and skin conditions. It may also be used to treat other conditions as determined by your doctor.

Before Using This Medicine:

Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are also taking mifepristone. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are using amphotericin B, anticholinesterase medicines (eg, neostigmine), or if you are taking barbiturates (eg, phenobarbital), birth control pills, clarithromycin, cyclosporine, digoxin, certain diuretics (eg, hydrochlorothiazide or furosemide), ephedrine, estrogens, interleukin-2, ketoconazole, non-steroidal anti-inflammatory medicines (eg, naproxen or ibuprofen), rifampin, salicylates (eg, aspirin), medicine for seizures (eg, carbamazepine or phenytoin), methotrexate, quinolones (eg, ciprofloxacin), ritodrine, tacrolimus, or warfarin. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions including a history of cirrhosis; diabetes; unexplained diarrhea; glaucoma; heart problems (eg, congestive heart failure, heart attack); high blood pressure; current or recent bacterial, fungal, protozoal, threadworm, or viral infection; tuberculosis; kidney problems; osteoporosis; myasthenia gravis; mental or mood problems; esophagus, stomach, or bowel problems (eg, diverticulitis, ulcers, ulcerative colitis, or recent surgery); thyroid problems; swelling; adrenal gland problems; allergies; pregnancy; breast-feeding; or if you are on a low salt diet. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have a systemic fungal infection, inflammation of the eye nerve (optic neuritis), herpes simplex infection of the eye; a malarial infection in the brain, or if you are scheduled to receive a live or attenuated live vaccine (eg, smallpox). Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.

How to Use This Medicine:

Follow the directions for using this medicine provided by your doctor. TAKE THIS MEDICINE with food or a snack. Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure this dose. Consult your prescription label or packaging for storage requirements. Ask your pharmacist for more information if needed. IF YOU MISS A DOSE OF THIS MEDICINE and you are taking 1 dose daily, take it as soon as possible. If you do not remember until the next day, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.


DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to it or are allergic to any ingredient in this product. DO NOT STOP TAKING THIS MEDICINE without checking with your doctor. Laboratory and/or medical tests, including blood pressure checks, blood glucose checks, physical exams, eye exams, and bone density tests may be performed to monitor your progress or to check for side effects. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are taking this medicine. THIS MEDICINE MAY AFFECT CERTAIN LAB TEST RESULTS, such as allergy skin tests. Make sure laboratory personnel and your doctors know you use this medicine. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, OR SURGERY, tell the doctor or dentist that you are using this medicine. CORTICOSTEROIDS MAY LOWER YOUR ABILITY TO FIGHT INFECTION or may cause infections to be more severe. The risk may be greater if you take them for a long time. Avoid contact with people who have infections such as colds, chickenpox, measles, or tuberculosis (TB). Tell your doctor right away if you have contact with anyone who has these infections. Tell your doctor if you develop symptoms such as fever, sore throat, rash, or chills. Check with your doctor if you have questions about your risk of infection. CHECK WITH YOUR DOCTOR BEFORE HAVING IMMUNIZATIONS (VACCINATIONS) while you are using this medicine. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. IF YOU HAVE OSTEOPOROSIS (weak bones) or if you are at risk for developing osteoporosis, be sure you have enough calcium and vitamin D in your diet while you are taking this medicine. If you have questions about your risk for osteoporosis or whether you may need to take a calcium or vitamin D supplement while you take this medicine, talk with your doctor. CORTICOSTEROID MEDICINES MAY AFFECT growth rate in children and adolescents in some instances. Your child's growth may need to be checked regularly while using this medicine. CAUTION IS ADVISED WHEN USING THIS MEDICINE IN THE ELDERLY because they may be more sensitive to the effects of the medicine especially osteoporosis (weak bones). FOR WOMEN: IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy. THIS MEDICINE IS EXCRETED in breast milk. IF YOU ARE OR WILL BE BREAST-FEEDING while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby. IF YOU HAVE DIABETES, this medicine may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.

Possible Side Effects:

SIDE EFFECTS that may occur while you are taking this medicine include difficulty sleeping, dizziness, flushing, nervousness, increased appetite, increased sweating, indigestion, or nausea. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience bone problems (such as bone pain, or broken or fractured bones); chronic back pain; changes in body fat; changes in menstrual periods; headache; muscle aches or weakness; fever, chills, or persistent sore throat; vision changes or other eye problems; or unusual weight gain. CONTACT YOUR DOCTOR IMMEDIATELY if you experience swelling of feet, hands, or legs; black, tarry stools; increased hunger, thirst, or urination; mood, mental, or personality changes; seizures; severe muscle pain or weakness; skin growths; severe dizziness or headache; severe stomach pain, nausea, or vomiting; unusual bruising or bleeding; thinning of skin; or vomit that looks like coffee grounds. An allergic reaction to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, dizziness, or trouble breathing. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


If overdose is suspected, contact your local poison control center or emergency room immediately.

Additional Information:

DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.

Copyright 2015 Wolters Kluwer Health, Inc.


- This information is not intended to substitute for professional medical advice. Be sure to contact your physician, pharmacist or other health care provider for more information about this medication. By searching these web site pages, you agree to our terms and conditions of use.