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Drug Information For:


Ingredient Name:

HYDROMORPHONE (hye-droe-MOR-fone)

Drug Manufacturer:


Common Uses:

This medicine is a narcotic (opioid) analgesic used to treat pain in certain patients.

Before Using This Medicine:

WARNING: This medicine is a narcotic pain reliever that may become habit-forming. Do NOT exceed the recommended dose, take for longer than prescribed, or take more often than prescribed without checking with your doctor. THIS MEDICINE MAY ALSO CAUSE SEVERE BREATHING PROBLEMS. This effect may be worse if you take it with alcohol, with other narcotic pain relievers, or with certain other medicines. Ask your doctor or pharmacist if you have questions about which medicines may add to this effect. Contact your doctor right away if you experience slow or shallow breathing. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are also taking sodium oxybate (GHB). ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking anticholinergics (eg, oxybutynin, scopolamine), mixed agonist/antagonist pain medicines (eg, buprenorphine, butorphanol, pentazocine), naltrexone, other narcotic pain relievers (eg, codeine, morphine, oxycodone), phenothiazines (eg, chlorpromazine), or tricyclic antidepressants (eg, amitriptyline). Tell your doctor if you are taking a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) or have taken one within the last 14 days. DO NOT START OR STOP any medicine without doctor or pharmacist approval. INFORM YOUR DOCTOR of any other medical conditions, including severe drowsiness, a recent head injury, growths in the brain (eg, lesions, tumors), increased pressure in the head, liver or kidney problems, gallbladder problems, pancreas problems, stomach or bowel problems (eg, inflammation, pseudomembranous colitis), stomach pain, allergies (including latex or sulfites), pregnancy, or breast-feeding. Tell your doctor if you have a history of heart problems (eg, cor pulmonale), low blood pressure, dehydration, low blood volume, chronic obstructive pulmonary disease (COPD) or other lung or breathing problems (eg, asthma, emphysema, bronchitis, sleep apnea), adrenal gland problems (eg, Addison disease), enlarged prostate, urinary blockage or trouble urinating, thyroid problems, seizures (eg, epilepsy), curvature of the spine, low blood oxygen levels (hypoxia), high blood carbon dioxide levels (hypercapnia), or recent stomach or bowel surgery. Tell your doctor if you have a personal or family history of mental or mood problems (eg, depression), alcohol or other substance abuse or dependence, or suicidal thoughts or attempts. Tell your doctor if you drink alcohol; have symptoms of alcohol withdrawal; are in poor health; will be having surgery; or are in shock caused by heart problems, blood vessel problems, or severe bleeding. USE OF THIS MEDICINE IS NOT RECOMMENDED if you are having an asthma attack. USE OF THIS MEDICINE IS NOTRECOMMENDED if you have difficult or slowed breathing, severe asthma, or known or suspected bowel blockage (paralytic ileus). Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.

How to Use This Medicine:

Follow the directions for using this medicine provided by your doctor. This medicine is usually given as an injection at your doctor's office, hospital, or clinic. IF YOU WILL BE USING THIS MEDICINE AT HOME, a health care provider will teach you how to use it. Be sure you understand how to use this medicine. Follow the procedures you were taught when you use a dose. Contact your health care provider if you have any questions. DO NOT USE THIS MEDICINE if it is cloudy or discolored, or if the vial is cracked or damaged. IF YOU HAVE BEEN USING THIS MEDICINE REGULARLY, do not suddenly stop using it without checking with your doctor. If you have been using this medicine for more than a few weeks and your doctor tells you to stop using it, your dose may need to be gradually lowered as directed by your doctor to avoid side effects. STORE THIS MEDICINE as directed on the prescription label. KEEP THIS PRODUCT, as well as syringes and needles, out of the reach of children and away from pets. IF THIS MEDICINE IS NO LONGER NEEDED, dispose of it as soon as possible. Ask your doctor or pharmacist how to dispose of this medicine properly. IF YOU ARE USING THIS MEDICINE FOR PERSISTENT PAIN, use it on a regular schedule to help control the pain more effectively. IF YOU MISS A DOSE OF THIS MEDICINE and you are using it regularly, use it as soon as possible. If it is nearing time for your next dose, do not double the dose to catch up, unless advised by your health care provider. Do not use 2 doses at once.


DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to it or if you are allergic to any ingredient in this product. BEFORE USING THIS MEDICINE, tell your doctor if you have had an allergic reaction to any other narcotic pain relievers (eg, codeine, morphine, oxycodone). If you have a question about whether you are allergic to this medicine or if a certain product is a narcotic pain reliever, contact your doctor or pharmacist. DO NOT EXCEED THE RECOMMENDED DOSE or take this medicine for longer than prescribed without checking with your doctor. Exceeding the recommended dose or taking this medicine for longer than prescribed may be habit-forming. Do not change your dose or use more often than prescribed without checking with your doctor. If using this medicine for an extended period of time, DO NOT SUDDENLY STOP taking this medicine without your doctor's approval. When used for an extended period of time or at high doses, this medicine may not work as well and may require different dosing. Talk with your doctor if this medicine stops working well. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, emergency care, or surgery, tell the doctor or dentist that you are using this medicine. SOME OF THESE PRODUCTS CONTAIN SULFITES. Sulfites may cause an allergic reaction in some patients (eg, asthma patients). If you have ever had an allergic reaction to sulfites, ask your pharmacist if your product has sulfites in it. THIS MEDICINE MAY CAUSE DROWSINESS, dizziness, blurred vision, or lightheadedness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. DO NOT DRINK ALCOHOL while you take this medicine. CHECK WITH YOUR DOCTOR before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you take this medicine; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness. THIS MEDICINE MAY CAUSE DIZZINESS, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness. IF YOUR PAIN CONTINUES or becomes worse, or if you have side effects that concern you, contact your doctor. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. CAUTION IS ADVISED WHEN USING THIS MEDICINE IN THE ELDERLY because they may be more sensitive to the effects of the medicine, especially drowsiness and breathing problems. FOR WOMEN: IF YOU THINK YOU MAY BE PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy.THIS MEDICINE IS EXCRETED IN BREAST MILK. Do not breast-feed while taking this medicine.

Possible Side Effects:

SIDE EFFECTS that may occur while using this medicine include dizziness, drowsiness, dry mouth, flushing, lightheadedness, nausea, sweating, or vomiting. If they continue or are bothersome, check with your doctor. THIS MEDICINE MAY CAUSE CONSTIPATION. To prevent constipation, maintain a diet adequate in fiber, drink plenty of water, and exercise. Talk to your doctor about using laxatives or stool softeners to prevent or treat constipation while you use this medicine. CONTACT YOUR DOCTOR IMMEDIATELY if you experience confusion; fainting; fast, slow, or irregular heartbeat; hallucinations; mental or mood changes; seizures; severe or persistent dizziness or drowsiness; severe or persistent constipation, headache, vomiting, or stomach pain; shallow, slowed, or difficult breathing; tremor; trouble urinating; uncontrolled eye movements; uncoordinated muscle movements; or vision changes (eg, blurred vision). AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash; hives; itching; difficulty breathing; tightness in the chest; or swelling of the mouth, face, lips, or tongue. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


IF OVERDOSE IS SUSPECTED, contact your local poison control center or emergency room immediately. Symptoms of overdose may include bluish skin; chest pain; cold and clammy skin; coma; excessive sweating; fainting; limp muscles; nausea and vomiting; pinpoint pupils; seizures; severe drowsiness or dizziness; slow or irregular heartbeat; or slow, shallow, or difficult breathing.

Additional Information:

DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for selecting an appropriate container and properly disposing of the container when it is full. CHECK WITH YOUR PHARMACIST about how to dispose of unused medicine.

Copyright 2014 Wolters Kluwer Health, Inc.


- This information is not intended to substitute for professional medical advice. Be sure to contact your physician, pharmacist or other health care provider for more information about this medication. By searching these web site pages, you agree to our terms and conditions of use.