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Drug Information For:
AMLODIPINE-BENAZ 5/10MG CAPSULES
Ingredient Name:AMLODIPINE (am-LOE-di-peen) and BENAZEPRIL (ben-AZ-e-pril)
Common Uses:This medicine is an angiotensin-converting enzyme (ACE) inhibitor and a calcium channel blocker combination used to treat high blood pressure.
Before Using This Medicine:WARNING: This medicine may cause birth defects or fetal or newborn death if you take it while you are pregnant. If you think you may be pregnant, contact your doctor right away. If you are planning to become pregnant, talk with your doctor about other treatment options. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are taking a medicine that contains aliskiren and you also have diabetes or kidney problems. Check with your doctor or pharmacist if you are not sure if a medicine you take contains aliskiren. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking aliskiren, angiotensin receptor blockers (ARBs) (eg, losartan), azole antifungals (eg, itraconazole, ketoconazole), clarithromycin, cobicistat, conivaptan, cyclosporine, dextran sulfate, diuretics (eg, furosemide, hydrochlorothiazide), eplerenone, everolimus, certain gold-containing medicines (eg, sodium aurothiomalate), insulin or oral diabetes medicine (eg, glyburide), lithium, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, celecoxib, ibuprofen, indomethacin), potassium-sparing diuretics (eg, spironolactone, triamterene), potassium supplements, probenecid, protease inhibitors (eg, ritonavir, telaprevir), simvastatin, sirolimus, trimethoprim, or other medicines for high blood pressure or heart failure. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including an autoimmune disease (eg, rheumatoid arthritis, lupus, scleroderma), bone marrow problems (eg, bone marrow suppression), low white blood cell levels, high blood potassium levels, low blood sodium levels, dehydration, low blood volume, low blood pressure, diabetes, allergies, pregnancy or if you are able to become pregnant, or breast-feeding. Tell your doctor if you have a history of heart attack or other heart problems (eg, heart failure, aortic stenosis, angina, coronary artery disease), blood vessel problems (eg, in the brain), blood flow problems, kidney problems (eg, renal artery stenosis), liver problems, or a kidney transplant. Tell your doctor if you drink alcohol, if you are on a low-salt (sodium) diet, if you are receiving treatments to reduce sensitivity to bee or wasp stings, you are scheduled to have surgery or receive anesthesia, or if you are receiving kidney dialysis or apheresis treatments. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have severe kidney problems, if you are pregnant, or if you have a history of angioedema (swelling of the hands, face, lips, eyes, throat, or tongue, difficulty swallowing or breathing, or unusual hoarseness). Contact your doctor or pharmacist if you have any questions orconcerns about taking this medicine.
How to Use This Medicine:Follow the directions for using this medicine provided by your doctor. An additional patient information leaflet is available with this medicine. Ask your doctor, nurse, or pharmacist any questions that you may have about this information. TAKE THIS MEDICINE with or without food. STORE THIS MEDICINE at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly-closed container, away from heat, moisture, and light. Do not store in the bathroom. KEEP THIS MEDICINE out of the reach of children and away from pets. Take this medicine regularly to receive the most benefit from it. Taking this medicine at the same time each day will help you to remember. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is within 12 hours of your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT take 2 doses at once.
Cautions:DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to any ingredient in this medicine or any ACE inhibitor (eg, lisinopril). IT MAY TAKE UP TO 2 WEEKS to receive the full benefits from this medicine. Do not change your dose or stop taking this medicine without checking with your doctor. LABORATORY AND/OR MEDICAL TESTS may be performed to monitor your progress or to check for side effects. Keep all doctor and laboratory appointments while you are taking this medicine. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, emergency care, or surgery, tell the doctor or dentist that you are taking this medicine. THIS MEDICINE MAY CAUSE DIZZINESS, LIGHTHEADEDNESS, OR FAINTING; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit or stand up slowly, especially in the morning. Sit or lie down at the first sign of any of these effects. These effects may be worse if you take this medicine with alcohol or certain medicines. Use this medicine with caution. DO NOT DRIVE, OPERATE MACHINERY, OR DO ANYTHING ELSE THAT COULD BE DANGEROUS until you know how you react to this medicine. IF YOU HAVE HIGH BLOOD PRESSURE, do not use nonprescription products that contain stimulants. These products may include diet pills or cold medicines. Contact your doctor if you have any questions or concerns. DO NOT USE A SALT SUBSTITUTE or potassium supplement without checking with your doctor. IF VOMITING, DIARRHEA, OR EXCESSIVE SWEATING OCCURS, you will need to take care not to become dehydrated. This could increase your risk of low blood pressure. Contact your doctor for instructions. A PERSISTENT, UNPRODUCTIVE COUGH may occur. Tell your doctor if this occurs. Recovery is usually rapid when the medicine is stopped. THIS MEDICINE MAY CAUSE A SERIOUS SIDE EFFECT CALLED ANGIOEDEMA. The risk may be higher in black patients. Contact your doctor at once if you develop swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness. Although rare, a component of this medicine (amlodipine) has been known to increase chest pain and increase the risk of a heart attack, especially in patients with severe heart disease. PATIENTS WHO TAKE MEDICINE FOR HIGH BLOOD PRESSURE often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal". Tell your doctor if you develop any new symptoms. THIS MEDICINE MAY NOT WORK AS WELL IN BLACK PATIENTS. Contact your doctor if your symptoms do not improve or if they become worse. WHILE YOU ARE USING THIS MEDICINE, brush and floss your teeth carefully. Also, have regular dental check-ups. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. CAUTION IS ADVISED WHEN USING THIS MEDICINE IN THE ELDERLY because they may be more sensitive to the effectsof the medicine. FOR WOMEN: This medicine may cause birth defects or fetal or newborn death if you take it while you are pregnant. If you think you may be pregnant, contact your doctor immediately. THIS MEDICINE IS EXCRETED IN BREAST MILK. DO NOT BREAST-FEED while taking this medicine.
Possible Side Effects:SIDE EFFECTS that may occur while taking this medicine include dizziness; headache; or persistent, dry cough. If they continue or are bothersome, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience blisters or sores in the mouth, nose, throat, or on the genitals; chest, jaw, or arm pain; dark urine; decreased urination; fainting; fast, slow, or irregular heartbeat; fever, chills, or persistent sore throat; flu-like symptoms; loss of appetite; muscle cramps, pain, or weakness; pale stools; red, swollen, blistered, or peeling skin; severe or persistent dizziness or light-headedness; severe or persistent nausea, diarrhea, or vomiting; shortness of breath; stomach pain; swelling of the hands, feet, or ankles; tender, bleeding, or swollen gums; unexplained weight gain; unusual bruising or bleeding; unusual sweating; unusual weakness or tiredness; wheezing; worsening of angina pain (eg, longer, more often, more severe); or yellowing of the skin or eyes. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash; hives; itching; difficulty swallowing or breathing; tightness in the chest; swelling of the mouth, hands, eyes, throat, face, lips, or tongue; unusual hoarseness. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Overdose:If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include dizziness, fast heartbeat, flushing of the skin, lightheadedness, or loss of consciousness.
Additional Information:DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. IF YOU WILL BE USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, be sure to obtain necessary refills before your supply runs out. CHECK WITH YOUR PHARMACIST about how to dispose of unused medicine.
Copyright 2015 Wolters Kluwer Health, Inc.