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Drug Information For:
AMITRIPTYLINE 25MG TABLETS
Ingredient Name:AMITRIPTYLINE (a-mee-TRIP-ti-leen)
Common Uses:This medicine is a tricyclic antidepressant used to treat depression. It may also be used to treat chronic pain and other conditions as determined by your doctor.
Before Using This Medicine:WARNING: ANTIDEPRESSANTS MAY INCREASE THE RISK OF SUICIDAL THOUGHTS OR ACTIONS in children, teenagers, and young adults. However, depression and certain other mental problems may also increase the risk of suicide. Talk with the patient's doctor to be sure that the benefits of using this medicine outweigh the risks. Family and caregivers must closely watch patients who take this medicine. It is important to keep in close contact with the patient's doctor. Tell the doctor right away if the patient has symptoms like worsened depression, suicidal thoughts, or changes in behavior. Discuss any questions with the patient's doctor. THIS MEDICINE IS NOT APPROVED FOR USE IN CHILDREN. Talk with the doctor. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are also taking cisapride. DO NOT TAKE THIS MEDICINE if you are taking or have taken linezolid or a monoamine oxidase inhibitor (eg, phenelzine) within the past 14 days. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking anticholinergics (eg, scopolamine), bupropion, carbamazepine, thyroid medicines (eg, levothyroxine), stimulants (eg, albuterol, pseudoephedrine), cimetidine, clonidine, SSRIs (eg, fluoxetine), valproic acid, fluconazole, guanethidine, guanfacine, warfarin, antihistamines (eg, diphenhydramine), droperidol, ketolides (eg, telithromycin), macrolides (eg, erythromycin), mibefradil, pimozide, streptogramins (eg, quinupristin/dalfopristin), terbinafine, a phenothiazine (eg, chlorpromazine), or methylene blue. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions including increased eye pressure or glaucoma, an irregular heartbeat, heart disease, chest pain, liver disease, prostate problems, thyroid disease, are unable to urinate (urinary retention), allergies, pregnancy, or breast-feeding. Tell your doctor if you have a history of seizures, epilepsy, porphyria, mental illness (eg, bipolar disorder, mania, manic-depression), or have considered or attempted suicide. Tell your doctor if you have alcoholism or regularly consume 3 or more alcoholic beverages per day. USE OF THIS MEDICINE IS NOT RECOMMENDED if you are recovering from a heart attack. Contact your doctor or pharmacist if you have any questions or concerns about using this medicine.
How to Use This Medicine:Follow the directions for taking this medicine provided by your doctor. This medicine has a MEDICATION GUIDE approved by the U.S. Food and Drug Administration. Read it carefully. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine. THIS MEDICINE MAY BE TAKEN WITH FOOD or on an empty stomach. STORE THIS MEDICINE at room temperature, below 86 degrees F (30 degrees C), in a tightly closed container away from heat, moisture, and light. Do not store in the bathroom. KEEP THIS MEDICINE out of the reach of children and away from pets. THIS MEDICINE MAY TAKE UP TO 30 DAYS TO CONTROL SYMPTOMS of depression. Continue to use this medicine even if you feel well. Do not miss any doses. IF YOU MISS A DOSE of this medicine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Cautions:DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to it or if you are allergic to any ingredient in this product. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are using this medicine. CHILDREN, TEENAGERS, AND ADULTS WHO TAKE THIS MEDICINE MAY BE AT INCREASED RISK FOR SUICIDAL THOUGHTS OR ACTIONS. Watch all patients who take this medicine closely. CONTACT THE DOCTOR AT ONCE if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. CONTACT YOUR DOCTOR AT ONCE if any signs of suicidal thoughts or actions occur. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, OR SURGERY, tell the doctor or dentist that you are using this medicine. THIS MEDICINE MAY CAUSE DIZZINESS, drowsiness, or blurred vision. DO NOT DRIVE, OPERATE MACHINERY, OR DO ANYTHING ELSE THAT COULD BE DANGEROUS until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. THIS MEDICINE MAY CAUSE DIZZINESS, lightheadedness, or fainting; alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of any of these effects. CHECK WITH YOUR DOCTOR before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using this medicine; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness. THIS MEDICINE MAY CAUSE increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to this medicine. Use a sunscreen or protective clothing if you must be outside for a prolonged period. DO NOT BECOME OVERHEATED in hot weather or during exercise or other activities since heatstroke may occur. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. CAUTION IS ADVISED WHEN USING THIS MEDICINE IN THE ELDERLY since they may be more sensitive to the effects, especially lightheadedness upon standing; rapid heartbeat; breathing problems; difficult urination; and constipation. FOR WOMEN: THIS MEDICINE HAS BEEN SHOWN TO CAUSE HARM to the human fetus. IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy. THIS MEDICINE IS EXCRETED IN BREAST MILK. DO NOT BREAST-FEED while taking this medicine. DIABETES PATIENTS: This medicine may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
Possible Side Effects:SIDE EFFECTS that may occur while you are taking this medicine include blurred vision; change in sexual desire or ability; constipation; diarrhea; dizziness; drowsiness; dry mouth; headache; loss of appetite; nausea; tiredness; trouble sleeping; or weakness. If they continue or are bothersome, check with your doctor. INVOLUNTARY AND UNCONTROLLABLE MOVEMENTS may develop in patients taking this medicine. Occurrence is highest among the elderly, especially women. The risk of developing these involuntary movements and the likelihood they will become permanent are increased with long-term use and with high doses. However, it is possible to develop these symptoms after short-term use at low doses. Contact your health care provider at once if any of the following occur: involuntary movements of the tongue, face, mouth, or jaw (eg, protrusion of tongue, puffing of cheeks, puckering of mouth, chewing movements), sometimes accompanied by involuntary movements of the arms and legs. SOME PEOPLE MAY BE AT RISK for eye problems from this medicine. Your doctor may want you to have an eye exam to see if you are at risk for these eye problems. Call your doctor right away if you have eye pain, vision changes, or swelling or redness in or around the eye. CONTACT YOUR DOCTOR IMMEDIATELY if you experience chest pain; confusion; dark urine; delusions; difficulty speaking or swallowing; fainting; fast or irregular heartbeat; fever, chills, or sore throat; hallucinations; new or worsening agitation, anxiety, panic attacks, aggressiveness, impulsiveness, irritability, hostility, exaggerated feeling of well-being, restlessness, or inability to sit still; numbness or tingling in an arm or leg; one-sided weakness; seizures; severe or persistent dizziness or headache; severe or persistent trouble sleeping; slurred speech; suicidal thoughts or actions; tremor; trouble urinating; unusual bruising or bleeding; unusual or severe mental or mood changes; or yellowing of the skin or eyes. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash; hives; itching; difficulty breathing; tightness in the chest; or swelling of the mouth, face, lips, or tongue. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Overdose:If overdose is suspected, contact your local poison control center or emergency room immediately.
Additional Information:DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. IF YOU WILL BE USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, be sure to obtain necessary refills before your supply runs out. CHECK WITH YOUR PHARMACIST about how to dispose of unused medicine.
Copyright 2015 Wolters Kluwer Health, Inc.