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Drug Information For:
INDOMETHACIN 50MG CAPSULES
Ingredient Name:INDOMETHACIN (in-doe-METH-a-sin)
Common Uses:This medicine is a nonsteroidal anti-inflammatory drug (NSAID) used to treat moderate to severe rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is used to treat gout, certain types of bursitis and tendonitis, or mild to moderate pain. It may also be used for other conditions as determined by your doctor.
Before Using This Medicine:WARNING: THIS MEDICINE is a nonsteroidal anti-inflammatory drug (NSAID). IT MAY CAUSE AN INCREASED RISK of serious and sometimes fatal heart and blood vessel problems (eg, heart attack, stroke). The risk may be greater if you already have heart problems or if you take this medicine for a long time. DO NOT USE THIS MEDICINE right before or after bypass heart surgery. THIS MEDICINE MAY CAUSE an increased risk of serious and sometimes fatal stomach ulcers and bleeding. Elderly patients may be at greater risk. This may occur without warning signs. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are also taking diflunisal, another NSAID (eg, ibuprofen), or triamterene. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking anticoagulants (eg, warfarin), angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), angiotensin receptor blockers (eg, losartan), beta-blockers (eg, propranolol), corticosteroids (eg, prednisone), cyclophosphamide, cyclosporine, digoxin, diuretics (eg, furosemide, hydrochlorothiazide), heparin, lithium, methotrexate, potassium-sparing diuretics (eg, spironolactone, triamterene), probenecid, quinolones (eg, ciprofloxacin), salicylates (eg, aspirin), selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), or sulfonylureas (eg, glipizide). DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including if you have a history of kidney or liver disease, diabetes, stomach or bowel problems (eg, bleeding, perforation, ulcers, inflammation), swelling or fluid buildup, depression, mental or mood problems, seizures, Parkinson disease, asthma, growths in the nose (nasal polyps), mouth inflammation, allergies, pregnancy, or breast-feeding. Tell your doctor if you have poor health, dehydration or low fluid volume, low blood sodium levels, high blood potassium levels, drink alcohol, or have a history of alcohol abuse. Tell your doctor if you have high blood pressure, a blood disorder, bleeding or clotting problems, heart problems (eg, heart failure), blood vessel disease, or if you are at risk for any of these diseases. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have recently had or will be having bypass heart surgery, or if you are more than 29 weeks pregnant. Contact your doctor or pharmacist if you have any questions about taking this medicine.
How to Use This Medicine:Follow the directions for using this medicine provided by your doctor. This medicine may come with a medication guide. Read it carefully. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine. TAKE THIS MEDICINE with a full glass of water (8 oz/240 mL) as directed by your doctor. TAKE THIS MEDICINE with food. Taking it with food may not decrease the risk of stomach or bowel problems (such as bleeding or ulcers) that may occur while taking this medicine. Talk with your doctor or pharmacist if you experience persistent stomach upset. STORE THIS MEDICINE at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), away from heat, moisture, and light. Store in the original container. Do not store in the bathroom. KEEP THIS MEDICINE out of the reach of children and away from pets. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Cautions:DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to it or if you are allergic to any ingredient in this product. DO NOT TAKE THIS MEDICINE if you have had a severe allergic reacton (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or an NSAID (eg, ibuprofen, celecoxib). DO NOT TAKE MORE THAN THE RECOMMENDED DOSE or use for longer than prescribed without checking with your doctor. Laboratory and/or medical tests, including kidney function, liver function, complete blood cell counts, and blood pressure, may be performed to monitor your progress or to check for side effects. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are taking this medicine. THIS MEDICINE MAY INTERFERE with certain lab tests. Be sure your doctor and lab personnel know that you take this medicine. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, OR SURGERY, tell the doctor or dentist that you are taking this medicine. THIS MEDICINE MAY CAUSE dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use this medicine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. SERIOUS STOMACH ULCERS OR BLEEDING can occur with the use of this medicine. Taking it in high doses or for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking this medicine with food will NOT reduce the risk of these effects. Contact your doctor or emergency room at once if you develop severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling. SERIOUS AND SOMETIMES FATAL SKIN REACTIONS (eg, Stevens-Johnson syndrome, toxic epidermal necrolysis) may happen with this medicine. Get medical help right away if you develop a rash; red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes. THIS MEDICINE is an NSAID. Before you start taking any new medicine, read the ingredients. If it also has an NSAID (eg, ibuprofen) in it, check with your doctor. If you are not sure, check with your doctor or pharmacist. DO NOT TAKE ASPIRIN while you are using this medicine unless your doctor tells you to. USE THIS MEDICINE WITH CAUTION in the ELDERLY; they may be more sensitive to its effects, including stomach bleeding, kidney problems, confusion, or mental changes. FOR WOMEN: THIS MEDICINE MAY HARM THE FETUS. DO NOT USE it if you are more than 29 weeks pregnant. IF YOU THINK YOU MAY BE PREGNANT, contact your doctor. You will need to discuss the benefits and risks of using this medicine while you are pregnant. THIS MEDICINE IS FOUND IN BREAST MILK. DO NOT BREAST-FEED while you are taking this medicine.
Possible Side Effects:SIDE EFFECTS that may occur while taking this medicine include constipation; diarrhea; dizziness; drowsiness; gas; headache; heartburn; nausea; stomach pain or upset; or vomiting. If they continue or are bothersome, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience blood in the urine; bloody or black, tarry stools; change in the amount of urine produced; chest pain; confusion; depression; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; mental or mood changes; numbness of an arm or leg; one-sided weakness; rectal bleeding; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; severe headache or dizziness; severe or persistent stomach pain or nausea; severe vomiting; shortness of breath; sudden or unexplained weight gain; swelling of hands, legs, or feet; symptoms of liver problems (eg, dark urine, flu-like symptoms, right upper stomach pain, unusual nausea or tiredness, yellowing of the skin or eyes); unusual bruising or bleeding; unusual joint or muscle pain; unusual tiredness or weakness; unusual vaginal bleeding; vision or speech changes; or vomit that looks like coffee grounds. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Overdose:If overdose is suspected, contact your local poison control center or emergency room immediately.
Additional Information:DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. IF YOU WILL BE USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, be sure to obtain necessary refills before your supply runs out. CHECK WITH YOUR PHARMACIST about how to dispose of unused medicine.
Copyright 2014 Wolters Kluwer Health, Inc.