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Drug Information For:

KINERET 100MG/0.67ML INJ, 0.67ML

Ingredient Name:

ANAKINRA (an-a-KIN-ra)

Drug Manufacturer:


Common Uses:

This medicine is an interleukin-1 (IL-1) blocker used to treat rheumatoid arthritis. It is also used to treat Neonatal-Onset Multisystem Inflammatory Disease (NOMID). This medicine may be used for other conditions as determined by your doctor.

Before Using This Medicine:

Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are also taking a tumor necrosis factor (TNF) blocking agent (eg, adalimumab). DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including kidney problems, an infection, weakened immune system, low white blood cell counts, low blood platelet levels, allergies, including rubber or latex, pregnancy, or breast-feeding. Tell your doctor if you have a history of serious infection or infection that keeps coming back, tuberculosis (TB) or a positive TB skin test or if you are planning to receive a vaccine. Contact your doctor or pharmacist if you have any questions about taking this medicine.

How to Use This Medicine:

Follow the directions for using this medicine provided by your doctor. An extra patient leaflet is available with this medicine. It also comes with detailed instructions for use. Read them carefully. Read them again each time you get this medicine refilled. Ask your doctor, nurse, or pharmacist any questions that you may have about this information. This medicine may be administered as an injection at your doctor's office, hospital, or clinic. IF YOU ARE USING THIS MEDICINE AT HOME, a healthcare professional will provide detailed instructions for appropriate use. Ask them any questions that you may have about your medicine or giving injections. If the medicine contains particles or if the container is cracked or damaged in any way, do not use it. DO NOT SHAKE this medicine. USE THE PROPER TECHNIQUE taught to you by your doctor. Inject deep under the skin, NOT into muscle or a vein. Rotate injection sites. DO NOT INJECT this medicine into an area that is irritated, bruised, red, infected, or scarred, or has stretch marks. This medicine should be administered at the same time each day. Wash your hands thoroughly with soap and warm water before using this medicine. BEFORE USING THIS MEDICINE, take it out of the refrigerator and leave it at room temperature for 30 minutes. Use a new syringe every day. Use the prefilled syringe only once. Throw away any unused portion of the medicine. Do not save for future use. Do not use a syringe that has been dropped or broken. Properly dispose of the damaged syringe and replace it with the syringe that would be used on the last day of the week in your current box. For example, if you start on Wednesday, the last day of the week in your series is Tuesday. After using all of the remaining syringes in your current box, start your next box. STORE UNOPENED SYRINGES OF THIS MEDICINE in the refrigerator, between 36 and 46 degrees F (2 to 8 degrees C). Do not freeze. Do not use a syringe that has been left at room temperature for more than 24 hours. Do not use this medicine beyond the expiration date on the container. Do not store in the bathroom. KEEP THIS PRODUCT, as well as syringes and needles, out of the reach of children and pets. IF YOU MISS A DOSE OF THIS MEDICINE, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. DO NOT use 2 doses on the same day.


DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to it or if you are allergic to any ingredient in this product or you are allergic to proteins derived from Escherichia coli (E. coli). DO NOT EXCEED THE RECOMMENDED DOSE or use this medicine for longer than prescribed without checking with your doctor. LABORATORY AND/OR MEDICAL TESTS, including white blood cell counts, may be performed to monitor your progress or to check for side effects. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are using this medicine. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, OR SURGERY, tell the doctor or dentist that you are taking this medicine. Anakinra may put your body at an increased risk for serious infections. THIS DRUG IS NOT RECOMMENDED if you have an infection or an infection-related illness (eg, pneumonia, tuberculosis). Tell your doctor if you have, or if you develop, any symptoms of an infection such as fever, persistent sore throat, productive cough (eg, sputum-producing), or unusual weakness. The risk of developing serious infections is even greater if you are also using a tumor necrosis factor medicine such as etanercept. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. Avoid vaccinations with live virus vaccines (eg, measles, mumps, oral polio) while you are taking this medicine. Check with your doctor before having any vaccinations while you are using this medicine. FOR WOMEN: IF YOU BECOME PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy. IT IS UNKNOWN IF THIS MEDICINE IS EXCRETED in breast milk. IF YOU ARE OR WILL BE BREAST-FEEDING while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby.

Possible Side Effects:

SIDE EFFECTS that may occur while using this medicine include diarrhea, flu-like symptoms, headache, nausea, reaction at the injection site (eg, redness, swelling, bruising, itching, pain, stinging), runny nose, sinus inflammation, sore throat, stomach pain, upper respiratory tract infection, or vomiting. If they continue or are bothersome, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience fainting; fast heartbeat; swelling; symptoms of infection (fever, chills, or persistent cough or sore throat; increased or painful urination; open sores on your body; warm, red, or swollen skin); unexplained bone or joint pain; unusual bruising or bleeding; unusual sweating; or wheezing. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash; hives; itching; difficulty breathing; tightness in the chest; unusual hoarseness; swelling of the mouth, face, lips, throat, or tongue. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


IF OVERDOSE IS SUSPECTED, contact your local poison control center or emergency room immediately.

Additional Information:

DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for selecting an appropriate container and properly disposing of the container when it is full. CHECK WITH YOUR PHARMACIST about how to dispose of unused medicine.

Copyright 2015 Wolters Kluwer Health, Inc.


- This information is not intended to substitute for professional medical advice. Be sure to contact your physician, pharmacist or other health care provider for more information about this medication. By searching these web site pages, you agree to our terms and conditions of use.