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Drug Information For:
MACRODANTIN 25MG CAPSULES
Ingredient Name:NITROFURANTOIN (NYE-troe-fure-AN-toin)
Drug Manufacturer:PROCTER & GAMBLE
Common Uses:This medicine is an antibiotic used for treating and preventing urinary tract infections caused by certain bacteria.
Before Using This Medicine:Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking probenecid or sulfinpyrazone. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including anemia, diabetes, blood electrolyte problems, glucose-6-phosphate dehydrogenase (G6PD) deficiency, kidney problems, liver problems, nerve problems (eg, peripheral neuropathy), porphyria (a certain blood problem), low levels of vitamin B in your blood, allergies, pregnancy, or breast-feeding. Tell your doctor if you have a history of lung problems (eg, diffuse interstitial pneumonitis, pulmonary fibrosis) or if you have very poor health. USE OF THIS MEDICINE IS NOT RECOMMENDED if you are pregnant and at term (38 to 42 weeks pregnant), you are about to go into labor, or you are in labor; if you have decreased kidney function, decreased urination, or you are unable to urinate; or if you have a history of liver problems or yellowing of the skin or eyes after taking any form of this medicine. This medicine should not be used in CHILDREN younger than 1 month old; the risk of anemia may be greater in these children. Contact your doctor or pharmacist if you have any questions or concerns about using this medicine.
How to Use This Medicine:Follow the directions for taking this medicine provided by your doctor. TAKE THIS MEDICINE by mouth with food. DRINKING EXTRA FLUIDS while you are taking this medicine is recommended. Check with your doctor for instructions. DO NOT TAKE AN ANTACID THAT HAS MAGNESIUM TRISILICATE in it while you are taking this medicine. Check with your pharmacist if you are unsure which antacids have magnesium trisilicate in them. STORE THIS MEDICINE at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), away from heat, moisture, and light. Do not store in the bathroom. KEEP THIS MEDICINE out of the reach of children and away from pets. TO CLEAR UP YOUR INFECTION COMPLETELY, take this medicine for the full course of treatment. Keep taking it even if you feel better in a few days. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make your infection harder to treat in the future. IF YOU MISS A DOSE of this medicine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Cautions:DO NOT USE THIS MEDICINE IF you are allergic to any ingredient in this medicine. LAB TESTS may be performed while you use this medicine. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. THIS MEDICINE MAY CAUSE DROWSINESS OR DIZZINESS. These effects may be worse if you take it with alcohol or certain medicines. Use this medicine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. THIS MEDICINE MAY RARELY CAUSE SEVERE AND SOMETIMES FATAL LUNG PROBLEMS. If this occurs, it is usually in patients who take this medicine for 6 months or longer. These problems may occur without warning signs. If you will be using this medicine for a long period of time, your doctor may perform lung function tests to check for side effects. Tell your doctor right away if you develop fever, chills, chest pain, unusual cough, trouble breathing (especially while you are being active), other breathing problems, or persistent feeling of being unwell. THIS MEDICINE MAY RARELY CAUSE SEVERE AND SOMETIMES FATAL LIVER PROBLEMS. Tell your doctor right away if you develop yellowing of the skin or eyes; pale stools; or severe or persistent nausea, loss of appetite, or stomach pain. THIS MEDICINE MAY RARELY CAUSE SEVERE AND SOMETIMES FATAL NERVE PROBLEMS. The risk may be greater in patients who have decreased kidney function, anemia, diabetes, electrolyte problems, or low blood vitamin B levels. Tell your doctor right away if you develop numbness, burning, or tingling in the hands or feet. MILD DIARRHEA IS COMMON WITH ANTIBIOTIC USE. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor. LONG-TERM OR REPEATED USE OF THIS MEDICINE may cause a second infection. Tell your doctor if signs of a second infection occur. THIS MEDICINE MAY DISCOLOR THE URINE. This is normal and not a cause for concern. BEFORE YOU BEGIN TAKING ANY NEW MEDICINES, either prescription or over-the-counter, check with your doctor or pharmacist. Use this medicine with caution in the ELDERLY; they may be more sensitive to its effects. FOR WOMEN: IF YOU BECOME PREGNANT, contact your doctor. You will need to discuss the benefits and risks of using this medicine while you are pregnant. DO NOT TAKE THIS MEDICINE IF you are at term (38 to 42 weeks pregnant), if you are about to go into labor, or if you are in labor. THIS MEDICINE IS FOUND in breast milk. DO NOT BREAST-FEED infants younger than 1 month old while you are taking this medicine. If your child is older than 1 month, check with your doctor beforebreastfeeding to discuss the risks to your baby. DIABETES PATIENTS: This medicine may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.
Possible Side Effects:SIDE EFFECTS that may occur while taking this medicine include gas; headache; loss of appetite; mild diarrhea; or nausea. If they continue or are bothersome, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience bloody or watery stools; bluish skin or nails; blurred vision or other vision changes (eg, vision loss); butterfly-shaped rash on the nose and cheeks; confusion; eye pain; joint or muscle pain; mood or mental changes (eg, depression); persistent feeling of being unwell; severe or persistent headache; red, swollen, blistered, or peeling skin; severe or persistent diarrhea; severe stomach pain or cramps; symptoms of liver problems (eg, yellowing of the skin or eyes, dark urine, pale stools, severe or persistent nausea or loss of appetite, stomach pain); symptoms of lung problems (eg, fever, chills, chest pain, shortness of breath, unusual or persistent cough); tingling, numbness, or burning of the fingers and toes; unusual bruising or bleeding; or unusual tiredness or weakness. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Overdose:If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include vomiting.
Additional Information:DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out. CHECK WITH YOUR PHARMACIST about how to dispose of unused medicine.
Copyright 2014 Wolters Kluwer Health, Inc.