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Drug Information For:


Ingredient Name:

MITOMYCIN (mye-toe-MYE-sin)

Drug Manufacturer:


Common Uses:

This medicine is an antineoplastic antibiotic used to treat certain cancers.

Before Using This Medicine:

WARNING: This medicine can cause severe blood disorders (e.g., bone marrow suppression, including hemolytic anemia, and especially thrombocytopenia and leukopenia). A syndrome known as Hemolytic Uremic Syndrome (a combination of anemia, decreased platelet count, and nonreversible kidney failure) has occurred. Blood transfusions may make the symptoms of this syndrome worse. Notify your doctor immediately if you develop symptoms of an infection (such as persistent sore throat or fever), fatigue, easy bleeding or bruising, dark urine, or change in amount of urine. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking tamoxifen. Inform your doctor of any other medical conditions, allergies, pregnancy, or breast-feeding. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.

How to Use This Medicine:

THIS MEDICINE IS USUALLY ADMINISTERED BY INJECTION at your doctor's office or a clinic. Ask your doctor, nurse, or pharmacist any questions you have about this medicine. IF NAUSEA, VOMITING, OR LOSS OF APPETITE OCCUR, ask your doctor, nurse, or pharmacist for ways to lessen these effects. STORE THIS MEDICINE as directed by the prescription label.


KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are being treated with this medicine. THIS MEDICINE LOWERS YOUR RESISTANCE to infection. To prevent infection, avoid contact with people who have colds or other infections. Do not touch your eyes or the inside of your nose unless you have thoroughly washed your hands first. THIS MEDICINE MAY REDUCE THE NUMBER OF BLOOD CELLS NEEDED FOR CLOTTING. To prevent bleeding, avoid situations where bruising or injury may occur. CHECK WITH YOUR DOCTOR BEFORE HAVING IMMUNIZATIONS (VACCINATIONS) while you are using this medicine. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS OR SURGERY, tell the doctor or dentist that you are taking this medicine. IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy. IT IS UNKNOWN IF THIS DRUG IS EXCRETED in breast milk. DO NOT BREAST-FEED while taking this medicine.

Possible Side Effects:

SIDE EFFECTS, that may go away during treatment, include nausea, loss of appetite, or hair loss. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience pain, redness, or swelling at the injection site; unusual bruising or bleeding; sores on the mouth or lips; dry cough, shortness of breath or difficulty breathing; fever or chills; or sore throat. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


If overdose is suspected, contact your local poison control center or emergency room immediately.

Additional Information:

This medicine may cause a serious reaction if it comes in contact with your skin. If this happens, wash the area with soap and water for approximately 15 minutes. Contact your doctor as soon as possible. The use of gloves while handling this medicine is recommended. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for selecting an appropriate container and properly disposing of the container when it is full.

Copyright 2014 Wolters Kluwer Health, Inc.


- This information is not intended to substitute for professional medical advice. Be sure to contact your physician, pharmacist or other health care provider for more information about this medication. By searching these web site pages, you agree to our terms and conditions of use.