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Drug Information For:


Ingredient Name:

ZOLPIDEM (zole-PI-dem)

Drug Manufacturer:


Common Uses:

This medicine is a sedative-hypnotic (sleep medicine) used for short-term treatment of insomnia (trouble falling asleep).

Before Using This Medicine:

Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE IF you are taking sodium oxybate (GHB) or another medicine to help you sleep, including any other medicine that has zolpidem in it. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking benzodiazepines (eg, diazepam), chlorpromazine, ketoconazole, HIV protease inhibitors (eg, ritonavir), narcotic pain medicines (eg, hydrocodone, codeine), perampanel, sertraline, rifampin, or tricyclic antidepressants (eg, amitriptyline, imipramine). DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including kidney or liver problems, lung or breathing problems (eg, chronic obstructive pulmonary disease / COPD, sleep apnea), myasthenia gravis, metabolism problems, heart or blood pressure problems, very poor health, allergies, pregnancy, or breast-feeding. Tell your doctor if you have a history of mood or mental problems (eg, depression), suicidal thoughts or behaviors, or alcohol or substance abuse or addiction. This medicine should not be used in CHILDREN younger than 18 years old; safety and effectiveness in children have not been confirmed. Children may be more sensitive to this medicine's side effects, especially dizziness, headache, and hallucinations. Contact your doctor or pharmacist if you have any questions about taking this medicine.

How to Use This Medicine:

Follow the directions for taking this medicine provided by your doctor. This medicine comes with a MEDICATION GUIDE approved by the U.S. Food and Drug Administration. Read it carefully each time you refill this medicine. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine. TAKE THIS MEDICINE on an empty stomach at least 2 hours after a meal. This medicine works very quickly; use this medicine right before going to sleep. Use this medicine only when you are able to get a full night's sleep (7 to 8 hours). STORE THIS MEDICINE at room temperature, between 68 and 77 degrees F (20 and 25 degrees C) away from heat, moisture, and light. Do not store in the bathroom. KEEP THIS MEDICINE out of the reach of children and away from pets. IF YOU MISS A DOSE OF THIS MEDICINE, skip the missed dose and go back to your regular dosing schedule. DO NOT take 2 doses at once. Do not take more than your total daily dose in any 24-hour period.


DO NOT USE THIS MEDICINE IF you are allergic to any ingredient in this medicine or to any other medicine that has zolpidem in it. WHEN SLEEP MEDICINES ARE TAKEN EVERY NIGHT for more than a few weeks, they may lose their effectiveness. This is known as TOLERANCE. Sleep medicines should usually be used only for short periods of time, such as a few days and generally no longer than 1 or 2 weeks. If your sleep problems continue, contact your doctor. DO NOT EXCEED THE RECOMMENDED DOSE or take this medicine for longer than prescribed. Doing so may be habit-forming. If using this medicine for an extended period of time, DO NOT SUDDENLY STOP taking this medicine without your doctor's approval. THIS MEDICINE MAY CAUSE drowsiness, dizziness, blurred vision, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use this medicine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. DO NOT TAKE THIS MEDICINE if you drank alcohol that day or before bed, or if you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using this medicine; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness. THIS MEDICINE MAY CAUSE a "carryover" effect on you the day after you take it. The risk may be increased if you take it with less than a full night's sleep (7 to 8 hours), if you take more than the recommended dose, or if you take it with certain other medicines. Do not drive or perform other tasks where you need to think clearly until you are fully alert. Discuss any questions or concerns with your doctor. SOME PATIENTS TAKING THIS MEDICINE have performed certain activities (eg, sleep-driving, making and eating food, making phone calls, having sex) while they were not fully awake. Patients often do not remember these events after they happen. Such an event may be more likely to occur if you use a high dose of this medicine or if you drink alcohol or take other medicines that may cause drowsiness while you use this medicine. Tell your doctor right away if such an event occurs. BEFORE YOU BEGIN TAKING ANY NEW MEDICINES, either prescription or over-the-counter, check with your doctor or pharmacist. Use this medicine with caution in the ELDERLY; they may be more sensitive to its effects, especially dizziness or drowsiness. FOR WOMEN: IF YOU THINK YOU MAY BE PREGNANT, contact your doctor. You will need to discuss the benefits and risks of using this medicine while you are pregnant. THIS MEDICINE MAY CAUSE PROLONGED SLEEP OR SEVERE BREATHING PROBLEMS IN THE NEWBORN if you take it during the last weeks of pregnancy, especially if you take it with certain other medicines. THIS MEDICINE IS FOUND in breast milk. IF YOU ARE OR WILL BE BREAST-FEEDING while you usethis medicine, check with your doctor. Discuss any possible risks to your baby.

Possible Side Effects:

SIDE EFFECTS that may occur while taking this medicine include diarrhea; dizziness; drowsiness (including daytime drowsiness); "drugged" feeling; dry mouth; headache; nausea; nose or throat irritation; stomach upset; tiredness; or weakness. If they continue or are bothersome, check with your doctor. THIS MEDICINE MAY CAUSE DROWSINESS and lowered level of alertness. This may lead to falls and injuries that may be severe. Severe injuries (eg, hip fracture, bleeding in the brain) have happened. Discuss any questions or concerns with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience abnormal thinking; behavior changes; breathing problems; chest pain; confusion; decreased coordination; fainting; fast or irregular heartbeat; hallucinations; memory problems (eg, memory loss); mental or mood changes (eg, aggression, agitation, anxiety); new or worsening depression; severe dizziness; severe or persistent nausea or vomiting; shortness of breath; suicidal thoughts or actions; or vision changes. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, eyes, throat, or tongue; throat closing; or unusual hoarseness. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


If overdose is suspected, contact your local poison control center or emergency room immediately.

Additional Information:

THIS MEDICINE IS USUALLY USED ONLY FOR A SHORT PERIOD OF TIME. If your symptoms do not get better within 7 to 10 days or if they get worse, check with your doctor. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. CHECK WITH YOUR PHARMACIST about how to dispose of unused medicine.

Copyright 2015 Wolters Kluwer Health, Inc.


- This information is not intended to substitute for professional medical advice. Be sure to contact your physician, pharmacist or other health care provider for more information about this medication. By searching these web site pages, you agree to our terms and conditions of use.