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Drug Information For:


Ingredient Name:

NIACIN (NYE-a-sin)

Drug Manufacturer:


Common Uses:

This medicine is an antihyperlipidemic used to improve cholesterol levels, reduce the risk for a second heart attack, slow or treat hardening of the arteries, and lower very high serum triglyceride levels. It is used in combination with diet. It may be used alone or with other medicines. It may also be used to treat other conditions as determined by your doctor.

Before Using This Medicine:

Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking anticoagulants (eg, warfarin); fibrates (eg, gemfibrozil, fenofibrate), HMG-CoA reductase inhibitors ("statins") (eg, simvastatin), medicine for high blood pressure (eg, clonidine, prazosin), or alcohol. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions including a history of chest pain, diabetes, gallbladder problems, glaucoma, gout, heart problems or a recent heart attack, kidney or liver problems, low blood pressure, low phosphate levels, muscle problems (eg, rhabdomyolysis), stomach problems (eg, peptic ulcers), thyroid problems, bleeding problems or if you are taking anticoagulants (eg, warfarin), allergies, pregnancy, or breast-feeding. Tell your doctor if you consume large amounts of alcohol. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have severe or unexplained liver problems, an active peptic ulcer, or a history of arterial bleeding. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.

How to Use This Medicine:

Follow the directions for using this medicine provided by your doctor. TO MINIMIZE FLUSHING AND UPSET STOMACH, take this medicine at bedtime after a low-fat snack (eg, low-fat yogurt, banana, crackers with a glass of milk) unless your doctor directs otherwise. DO NOT TAKE this medicine with alcohol, a hot drink, or spicy foods. DO NOT TAKE bile acid sequestrants (eg, colestipol, cholestyramine) within 4 to 6 hours of taking this medicine. STORE THIS MEDICINE at room temperature between 59 and 86 degrees F (15 and 30 degrees C) in a tightly-closed container, away from heat, moisture, and light. KEEP THIS MEDICINE out of the reach of children and away from pets. IF YOU MISS A DOSE OF THIS MEDICINE take it as soon as possible. If it almost time for the next dose, skip the missed dose and go back to your regular dosing schedule. DO NOT take 2 doses at once.


DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to it or if you are allergic to any ingredient in this product. DO NOT EXCEED THE RECOMMENDED DOSE without checking with your doctor. Laboratory and/or medical tests may be performed to monitor your progress or to check for side effects. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are taking this medicine. THIS MEDICINE MAY AFFECT CERTAIN LAB TEST RESULTS. Make sure laboratory personnel and your doctors know you take this medicine. THIS MEDICINE MAY CAUSE DIZZINESS OR LIGHTHEADEDNESS. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of these effects. DO NOT DRIVE, OPERATE MACHINERY, OR DO ANYTHING ELSE THAT COULD BE DANGEROUS until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. THIS MEDICINE MAY REDUCE THE NUMBER OF BLOOD CELLS THAT ARE NEEDED FOR CLOTTING. To prevent bleeding, avoid situations where bruising or injury may occur. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools. DO NOT SUBSTITUTE this medicine for any other type of niacin without talking with your doctor. Severe liver damage can occur. IF YOU STOP TAKING THIS MEDICINE for an extended period, contact your doctor before you start taking it again. Your dose may need to be adjusted. DO NOT TAKE large doses of vitamins while taking this medicine unless directed to by your doctor. FOLLOW THE DIETARY PLAN provided by your doctor. FLUSHING OCCURS WITH THIS MEDICINE and may last for several hours. Talk with your doctor if flushing becomes bothersome. TAKE THIS MEDICINE AT BEDTIME so that flushing will occur during sleep. If you are awakened by flushing at night, get up slowly, especially if you feel dizzy or faint or if you are taking blood thinners. Take aspirin or a nonsteroidal anti-inflammatory drug (NSAID) (eg, ibuprofen) 30 minutes before taking this medicine to lessen flushing. REPORT ANY UNEXPLAINED muscle pain, tenderness, or weakness to your doctor right away, especially if you also have a fever or general body discomfort. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. CAUTION IS ADVISED WHEN USING THIS MEDICINE IN THE ELDERLY because they may be more sensitive to the effects of the medicine. FOR WOMEN: IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy. THIS MEDICINE IS EXCRETED IN BREAST MILK. DO NOT BREAST-FEED while taking this medicine. IF YOU HAVE DIABETES, this medicine may affect your blood sugar or cause false test results with some urine glucose tests. Check bloodsugar levels closely. Check with your doctor before adjusting the dose of your diabetes medicine or changing your diet.

Possible Side Effects:

SIDE EFFECTS that may occur while taking this medicine include diarrhea; dizziness; headache; heartburn, increased cough, indigestion, or upset stomach; nausea, temporary skin redness, itching, tingling or feelings of warmth (flushing), or vomiting. CONTACT YOUR DOCTOR IMMEDIATELY if you experience black, tarry, or bloody stools; changes in vision (eg, cloudy or blurred vision); decrease in urine or dark-colored urine; fainting; fast or irregular heartbeat; flu-like symptoms (eg, chills, fever, persistent sore throat); increased sweating; loss of appetite; muscle pain, tenderness, swelling, or weakness (with or without fever and fatigue); numbness or persistent tingling of the skin; severe dizziness or headache; severe or persistent diarrhea, nausea or vomiting; shortness of breath; stomach pain; swelling of the hands, legs, or feet; unusual bruising or bleeding; vomit that looks like coffee grounds; or yellowing of the skin or eyes. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; or hoarseness. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms may include flushing.

Additional Information:

DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.

Copyright 2015 Wolters Kluwer Health, Inc.


- This information is not intended to substitute for professional medical advice. Be sure to contact your physician, pharmacist or other health care provider for more information about this medication. By searching these web site pages, you agree to our terms and conditions of use.