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Drug Information For:


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Common Uses:

This medicine is a narcotic (opioid) analgesic used to treat moderate to severe pain in patients who have already been taking and are tolerant to narcotic pain medicines. It may also be used to treat other conditions as determined by your doctor.

Before Using This Medicine:

WARNING: Morphine is available in several different concentrations. THIS CONCENTRATION SHOULD ONLY BE USED BY PATIENTS who have already been taking a narcotic pain medicine and are tolerant to its effects. Use of this medicine by people who are not used to taking narcotic pain medicines may cause severe and sometimes fatal breathing problems. BE SURE YOU UNDERSTAND how to measure your dose of this medicine. Discuss any questions or concerns with your doctor or pharmacist. KEEP THIS MEDICINE OUT OF THE REACH of children and away from pets. Seek emergency medical attention immediately if accidental ingestion occurs. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are also taking sodium oxybate (GHB) or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), or if you have taken an MAOI within the past 14 days. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking anticholinergics (eg, scopolamine, oxybutynin), antihistamines (eg, diphenhydramine), anti-nausea medicines (eg, ondansetron), benzodiazepines (eg, lorazepam), cimetidine, fluoxetine, ketorolac, mexiletine, mixed narcotic agonists/antagonists (eg, buprenorphine, butorphanol, pentazocine), naltrexone, other narcotic pain medicines (eg, hydrocodone), phenothiazines (eg, chlorpromazine), quinidine, rifamycins (eg, rifampin), risperidone, skeletal muscle relaxants (eg, cyclobenzaprine), sleep medicines (eg, zolpidem), tricyclic antidepressants (eg, amitriptyline), or trovafloxacin. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including asthma, chronic obstructive pulmonary disease (COPD), or other lung or breathing problems; increased pressure in the head; a recent head injury; growths in the brain (eg, tumors, lesions); severe drowsiness; low blood volume; stomach pain; very poor health; allergies; pregnancy; or breast-feeding. INFORM YOUR DOCTOR IF YOU HAVE a history of heart problems (eg, cor pulmonale), liver or kidney problems, thyroid problems, stomach or bowel problems (eg, constipation, blockage, inflammation), gallbladder or pancreas problems, prostate problems, trouble urinating, adrenal gland problems (eg, Addison disease), hypoxia (not enough oxygen in your body), hypercapnia or hypercarbia (high blood levels of carbon dioxide), curvature of the spine, seizures, mental or mood problems (eg, depression), hallucinations, suicidal thoughts or actions, alcohol or other substance abuse or dependence, or stomach or intestinal surgery. TELL YOUR DOCTOR if you will be having surgery; are currently in alcohol withdrawal; or if you are in shock caused by heart problems, blood vesselproblems, or severe bleeding. DO NOT USE THIS MEDICINE if you are having an asthma attack or if you drink alcohol. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have known or suspected bowel blockage (eg, paralytic ileus), severe or persistent diarrhea associated with antibiotic use (pseudomembranous colitis), slow or difficult breathing, severe asthma, or severe hypercarbia or hypercapnia. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.

How to Use This Medicine:

Follow the directions for using this medicine provided by your doctor. This medicine has a MEDICATION GUIDE approved by the U.S. Food and Drug Administration. Read it carefully. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine. This medicine may be taken on an empty stomach or with food. ONLY USE THE DROPPER THAT COMES WITH THIS MEDICINE to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose. This medicine contains a high concentration of morphine. BE SURE YOU UNDERSTAND how much medicine to use for your dose. Use extreme caution when you measure your dose of this medicine. Accidental overdose may cause serious and sometimes fatal side effects. IF YOU ALSO TAKE trovafloxacin, do not take it within 4 hours before or after taking this medicine. Check with your doctor if you have questions. STORE THIS MEDICINE at room temperature between 59 and 86 degrees F (15 and 30 degrees C), in a tightly-closed container, away from heat, moisture, and light. Keep this medicine out of the reach of children and away from pets. IF YOU MISS A DOSE OF THIS MEDICINE and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT take 2 doses at once.


DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to it or if you are allergic to any ingredient in this product. CHECK WITH YOUR DOCTOR BEFORE TAKING THIS MEDICINE if you have had a severe allergic reaction to any morphine or codeine related medicine (eg, hydrocodone, oxycodone, hydromorphone). If you have questions about whether you are allergic to this medicine or if a certain medicine is morphine or codeine related, contact your doctor or pharmacist. Laboratory and/or medical tests, including liver, kidney, and lung function, and complete blood cell counts, may be performed to monitor your progress or to check for side effects. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are taking this medicine. WHEN USED FOR AN EXTENDED PERIOD OF TIME, this medicine may not work as well and may require different dosing. Talk with your doctor if this medicine stops working well. DO NOT take more than the recommended dose or change your dose without first checking with your doctor. The risk of this medicine becoming habit-forming may be greater if you take it in high doses or for a long time. DO NOT SUDDENLY STOP taking this medicine without checking with your doctor. If you have been taking this medicine for more than a few weeks and your doctor tells you to stop using this medicine, your dose may need to be gradually lowered as directed by your doctor to avoid side effects. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, OR SURGERY, tell the doctor or dentist that you are using this medicine. AVOID ALCOHOL while you are using this medicine. CHECK WITH YOUR DOCTOR before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using this medicine; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness. THIS MEDICINE MAY CAUSE drowsiness, dizziness, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of these effects. DO NOT DRIVE, OPERATE MACHINERY, OR DO ANYTHING ELSE THAT COULD BE DANGEROUS until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. CAUTION IS ADVISED WHEN USING THIS MEDICINE IN THE ELDERLY because they may be more sensitive to the effects of the medicine, especially drowsiness or breathing problems. FOR WOMEN: IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy. THIS MEDICINE IS EXCRETED IN BREAST MILK. DO NOT BREAST-FEED while taking this medicine.

Possible Side Effects:

SIDE EFFECTS that may occur while using this medicine include dizziness, drowsiness, headache, lightheadedness, nausea, restless mood, sweating, or vomiting. If they continue or are bothersome, check with your doctor. CONSTIPATION IS A COMMON SIDE EFFECT of this medicine. To prevent constipation, maintain a diet adequate in fiber, drink plenty of water, and exercise. Talk to your doctor about using fiber laxatives or stool softeners to prevent or treat constipation while you use this medicine. CONTACT YOUR DOCTOR IMMEDIATELY if you experience confusion; disorientation; fainting; fast, slow, or irregular heartbeat; hallucinations; mental or mood changes (eg, agitation, exaggerated sense of well-being); seizures; severe or persistent constipation or stomach pain; severe or persistent dizziness, drowsiness, or headache; shortness of breath; slow or shallow breathing; sudden chest pain; swelling of the hands, ankles, or feet; trouble urinating; unusual bruising or bleeding; unusual tiredness or weakness; or vision changes (eg, blurred vision). AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash; hives; itching; difficulty breathing; tightness in the chest; or swelling of the mouth, face, lips, throat, or tongue. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


IF OVERDOSE IS SUSPECTED, contact your local poison control center or emergency room immediately. Symptoms of overdose may include bluish skin or nails; cold and clammy skin; coma; confusion; decreased muscle tone; decreased pupil size; loss of consciousness; low body temperature; seizures; severe drowsiness, dizziness, or lightheadedness; severe muscle pain or weakness; shortness of breath; slow heartbeat; slow or shallow breathing.

Additional Information:

DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out. IF THIS MEDICINE IS NO LONGER NEEDED, dispose of it as soon as possible. CHECK WITH YOUR PHARMACIST about how to dispose of unused medicine.

Copyright 2015 Wolters Kluwer Health, Inc.


- This information is not intended to substitute for professional medical advice. Be sure to contact your physician, pharmacist or other health care provider for more information about this medication. By searching these web site pages, you agree to our terms and conditions of use.