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Common Uses:

This medicine is a progestin hormone used to prevent pregnancy. It may also be used to treat other conditions as determined by your doctor.

Before Using This Medicine:

WARNING: THIS MEDICINE MAY CAUSE YOU TO LOSE CALCIUM FROM YOUR BONES. This could reduce bone strength. This effect is greater if you use this medicine for a long time. Your bones may not recover completely after you stop using it. If you use this medicine continuously for more than 2 years, you may have an increased risk for weak, porous bones (osteoporosis). This could increase the risk of broken bones, especially after menopause. It is not known if the risk of developing weak bones is grater in teenagers or young adults who use this medicine. THIS MEDICINE SHOULD NOT BE USED AS A LONG-TERM BIRTH CONTROL METHOD (more than 2 years) unless other birth control methods are not right for you. Talk with your doctor for more information. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking aprepitant, barbiturates (eg, phenobarbital), bosentan, carbamazepine, felbamate, griseofulvin, HIV protease inhibitors (eg, ritonavir), nonnucleoside reverse transcriptase inhibitor (NNRTI) (eg, nevirapine), oxcarbazepine, phenytoin, rifamycins (eg, rifampin), St. John's wort, or topiramate. You will need to use another form of birth control (eg, condoms) if you take any of these medicines while using this medicine. Tell your doctor if you are taking medicines that can weaken the bones, such as anticonvulsants (eg, phenytoin) or corticosteroids (eg, prednisone). DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including a history of seizures, migraine headaches, asthma, heart problems (eg, congestive heart failure), high blood pressure, kidney problems, mental or mood problems (eg, depression), diabetes, menstrual changes (eg, irregular or lighter menstrual periods), fibrocystic breast disease, lumps in your breast, bleeding from the nipples, abnormal mammogram, family history of breast cancer, allergies, pregnancy, or breast-feeding. Tell your doctor if you have bone problems (eg, weak bones, osteoporosis), a certain eating disorder (anorexia nervosa), or if a family member has had bone problems (eg, osteoporosis). Tell your doctor if you drink alcohol or use tobacco regularly. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have undiagnosed vaginal bleeding, or a history of breast cancer, stroke or bleeding in the brain, liver problems, blood clots, or problems with blood vessels in your brain. USE OF THIS MEDICINE IS NOT RECOMMENDED if you are pregnant or think you may be pregnant. Use of this medicine in CHILDREN who have not had their first menstrual period is not recommended. Discuss with your doctor the risks and benefits of giving thismedicine to your child. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.

How to Use This Medicine:

Follow the directions for using this medicine provided by your doctor. AN ADDITIONAL PATIENT INFORMATION LEAFLET is available with this medicine. Ask your doctor, nurse, or pharmacist any questions that you may have about this information. This medicine is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using this medicine at home, a health care provider will teach you how to use it. Be sure you understand how to use this medicine. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions. Do not use this medicine if it contains particles, is cloudy or discolored, or if the vial or syringe is cracked or damaged. This medicine is given every 3 months. It is very important that you return to your doctor's office for your next injection promptly at the end of the 3 month interval. BE SURE YOU KNOW WHEN YOU SHOULD BEGIN USING THIS MEDICINE according to your doctor's instructions. Discuss any questions or concerns with your doctor. STORE THIS MEDICINE as directed on the prescription label. KEEP THIS PRODUCT, as well as syringes and needles, out of the reach of children and pets. Use this medicine regularly to receive the most benefit from it. IF YOU MISS A DOSE OF THIS MEDICINE, contact your doctor as soon as possible.


DO NOT USE THIS MEDICINE if you have had an allergic reaction to it or are allergic to any ingredient in this product. This medicine does not stop the spread of HIV infection or other sexually transmitted diseases (STDs). Use barrier methods of birth control (eg, condoms) if you have HIV infection or an STD. Do not share needles, injection supplies, or items like toothbrushes or razors. Laboratory and/or medical tests may be performed to monitor your progress or to check for side effects. You should have a physical examination regularly as directed by your doctor while you are using this medicine. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are using this medicine. THIS MEDICINE MAY AFFECT CERTAIN LAB TEST RESULTS. Make sure laboratory personnel and your doctors know you are taking this medicine. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, OR SURGERY, tell the doctor or dentist that you are using this medicine. This medicine may take time to wear off after your last dose. You may not be able to become pregnant for several months after stopping this medicine. Discuss any questions or concerns with your doctor. This medicine may cause dizziness, drowsiness, lightheadedness, or vision changes. DO NOT DRIVE, OPERATE MACHINERY, OR DO ANYTHING ELSE THAT COULD BE DANGEROUS until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. THIS MEDICINE MAY CAUSE dark skin patches on your face. Exposure to the sun may make these patches darker. If patches develop, use a sunscreen or protective clothing when exposed to the sun, sunlamps, or tanning booths. THIS MEDICINE MAY CAUSE A DECREASE IN THE AMOUNT OF CALCIUM in your bones and make your bones weaker. This effect is of most concern during adolescence (teenage years) and early adulthood. If you need to use this medicine as a long-term birth control method (more than 2 years), your health care provider may test you for weak bones. CHECK WITH YOUR DOCTOR to see whether you should take a calcium and vitamin D supplement while you use this medicine. YOU MAY SKIP A MENSTRUAL PERIOD or your menstrual periods may stop while you use this medicine. If you have been receiving this medicine regularly every 3 months, you are probably not pregnant. However, if you think you may be pregnant, contact your doctor right away. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. FOR WOMEN: DO NOT USE THIS MEDICINE if you are pregnant. IF YOU THINK YOU MAY BE PREGNANT, contact your doctor immediately. THIS MEDICINE IS EXCRETED IN BREAST MILK. IF YOU ARE OR WILL BE BREAST-FEEDING while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby. DIABETES PATIENTS: This medicine may affectyour blood sugar. Check your blood sugar level closely and ask your doctor before adjusting the dose of your diabetes medicine.

Possible Side Effects:

SIDE EFFECTS that may occur while taking this medicine include weight gain; headache; weakness or tiredness; stomach pain or discomfort; nausea; trouble sleeping; dizziness; drowsiness; hot flashes; acne; nervousness; decreased interest in sex; leg cramps; or breast pain or tenderness. If they continue or are bothersome, check with your doctor. YOU MAY EXPERIENCE MENSTRUAL CYCLE CHANGES while using this medicine, including irregular or unpredictable bleeding or spotting, or an increase or decrease in menstrual bleeding. Contact your doctor right away if you experience unusually heavy or continuous bleeding, or any other severe or persistent menstrual changes. CHECK WITH YOUR DOCTOR IMMEDIATELY if you experience breast lumps or nipple bleeding; burning, numbness, or tingling; dark urine; fast heartbeat; fever; mental or mood changes (eg, depression); pale stools; partial or complete loss of vision or other changes in vision (eg, double vision); persistent loss of appetite; seizures; severe dizziness; sudden or severe headache or vomiting; fainting; sudden loss of coordination; slurred speech; swelling of the hands, ankles, or feet; weakness, numbness, or pain in the arms or legs; unusual tiredness or weakness; chest pain; shortness of breath; coughing up blood; pain, swelling, or tenderness in the calf or leg; severe stomach pain or tenderness; yellowing of the eyes or skin; or pain, pus, or bleeding at the injection site. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; or unusual hoarseness. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


If overdose is suspected, contact your local poison control center or emergency room immediately.

Additional Information:

DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for selecting an appropriate container and properly disposing of the container when it is full. CHECK WITH YOUR PHARMACIST about how to dispose of unused medicine.

Copyright 2015 Wolters Kluwer Health, Inc.


- This information is not intended to substitute for professional medical advice. Be sure to contact your physician, pharmacist or other health care provider for more information about this medication. By searching these web site pages, you agree to our terms and conditions of use.