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Drug Information For:
METFORMIN 500MG TABLETS
Ingredient Name:METFORMIN (met-FOR-min)
Common Uses:This medicine is a biguanide antidiabetic used along with a diet and exercise program to control high blood sugar in patients with type 2 diabetes. It may be used alone or with other antidiabetic medicines.
Before Using This Medicine:WARNING: THIS MEDICINE MAY RARELY CAUSE A SERIOUS AND SOMETIMES FATAL CONDITION CALLED LACTIC ACIDOSIS. The risk of lactic acidosis may be greater if you have liver problems, kidney problems, or heart failure. The risk may also be greater in patients who are elderly or who drink alcohol. DO NOT BEGIN TO TAKE THIS MEDICINE IF YOU ARE 80 YEARS OLD OR OLDER UNLESS LAB TESTS SHOW THAT YOU DO NOT HAVE DECREASED KIDNEY FUNCTION. CONTACT YOUR DOCTOR RIGHT AWAY IF YOU NOTICE SYMPTOMS SUCH AS muscle pain or tenderness, unusual drowsiness, dizziness or lightheadedness, slow or irregular heartbeat, fast or difficult breathing, unusual stomach discomfort, unusual weakness or tiredness, feeling of being unusually cold, or general feeling of being unwell. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking amiloride; beta-blockers (eg, propranolol); cimetidine; digoxin; morphine; procainamide; quinidine; quinine; ranitidine; triamterene; trimethoprim; vancomycin; calcium channel blockers (eg, nifedipine); corticosteroids (eg, prednisone); diuretics (eg, furosemide, hydrochlorothiazide); estrogen; hormonal contraceptives (eg, birth control pills); insulin; isoniazid; nicotinic acid; phenothiazines (eg, chlorpromazine); phenytoin; sulfonylureas (eg, glipizide); sympathomimetics (eg, albuterol, pseudoephedrine); thyroid hormones (eg, levothyroxine); or medicines that may harm the kidney (eg, aminoglycoside antibiotics, such as gentamicin; amphotericin B; tacrolimus). Ask your doctor if you are unsure if any of your medicines might harm the kidney. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor if you drink alcohol or have a history of heart problems, lung or breathing problems, thyroid problems, stomach or bowel problems (eg, paralysis, blockage), adrenal or pituitary problems, lactic acidosis, or alcohol abuse. Inform your doctor of any other medical conditions including vomiting, diarrhea, poor health or nutrition, low blood calcium or vitamin B12 levels, anemia, dehydration, infection, fever, recent injury, moderate to severe burns, upcoming surgery or certain lab procedures, allergies, pregnancy, or breast-feeding. TELL YOUR DOCTOR if you have heart failure, especially heart failure that is treated by medicine. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have a severe infection, low blood oxygen levels, kidney or liver problems, high blood ketone or acid levels (eg, diabetic ketoacidosis), dehydration, previous stroke, a recent heart attack, if you are in shock, or if you will be having surgery or certain lab procedures. IT IS NOT RECOMMENDED that you beginto take this medicine if you are 80 years old or more and have not had a kidney function test. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine. Use of this medicine in children under age 10 is not recommended. Discuss with your doctor the risks and benefits of giving this medicine to your child.
How to Use This Medicine:Follow the directions for using this medicine provided by your doctor. This medicine may come with a patient information leaflet. Read it carefully. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine. TAKE THIS MEDICINE with food. DRINK PLENTY OF FLUIDS while taking this medicine. STORE THIS MEDICINE at room temperature between 68 and 77 degrees F (20 and 25 degrees C), in a tightly-closed container, away from heat, moisture, and light. Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. KEEP THIS MEDICINE out of the reach of children and away from pets. Take this medicine regularly to receive the most benefit from it. Taking this medicine at the same times each day will help you to remember. CONTINUE TO TAKE THIS MEDICINE even if you feel well. Do not miss any doses. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. DO NOT take 2 doses at once.
Cautions:DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to it or are allergic to any ingredient in this product. THIS MEDICINE MAY COMMONLY CAUSE STOMACH UPSET, INDIGESTION, NAUSEA, VOMITING, OR DIARRHEA AT THE BEGINNING OF TREATMENT. If you develop unusual or unexpected stomach problems, or if you develop stomach problems later during treatment, contact your doctor at once. This may be a sign of lactic acidosis. IF VOMITING OR DIARRHEA OCCURS, you will need to take care not to become dehydrated. Contact your doctor for instructions. This medicine may cause dizziness. DO NOT DRIVE, OPERATE MACHINERY, OR DO ANYTHING ELSE THAT COULD BE DANGEROUS until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. THIS MEDICINE DOES NOT USUALLY CAUSE LOW BLOOD SUGAR (hypoglycemia). However, hypoglycemia may be more likely to occur if you take this medicine along with certain other medicines for diabetes (eg, sulfonylureas, insulin). It may also be more likely to occur if you skip a meal, exercise heavily, or drink alcohol. Signs of hypoglycemia include increased heartbeat, headache, chills, sweating, tremor, increased hunger, changes in vision, nervousness, weakness, dizziness, drowsiness, or fainting. It is a good habit to carry glucose tablets or gel to treat hypoglycemia. If you do not have a reliable source of glucose available, eat a quick source of sugar such as table sugar, honey, or candy, or drink a glass of orange juice or non-diet soda to quickly raise your blood sugar level. To prevent hypoglycemia, eat meals on a regular schedule and do not skip meals. DO NOT DRIVE OR PERFORM OTHER POSSIBLY UNSAFE TASKS IF YOU HAVE SYMPTOMS OF LOW BLOOD SUGAR. If you experience low blood sugar, tell your doctor. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are using this medicine. Laboratory and/or medical tests such as kidney function, liver function, fasting blood glucose, hemoglobin A1C, or blood counts, should be done to monitor your progress or to check for side effects. IF YOUR BLOOD SUGARS HAVE BEEN UNDER CONTROL AND ARE SUDDENLY DIFFICULT TO MANAGE, contact your doctor as soon as possible. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, LABORATORY TESTS, OR SURGERY, tell the doctor or dentist that you are using this medicine. During times of stress such as fever, infection, injury, or surgery, it may be more difficult to control your blood sugar. Consult your doctor, as a change in your medicine may be required. DO NOT drink large amounts of alcohol while you are taking this medicine. TALK TO YOUR DOCTOR BEFORE YOU DRINK ALCOHOL while you use this medicine. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. CAUTION ISADVISED WHEN USING THIS MEDICINE IN THE ELDERLY because they may be more sensitive to the effects of the medicine. Low blood sugar levels may be more difficult to recognize in the elderly. FOR WOMEN: IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy. IT IS UNKNOWN IF THIS MEDICINE IS EXCRETED in breast milk. IF YOU ARE OR WILL BE BREAST-FEEDING while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby.
Possible Side Effects:SIDE EFFECTS that may occur while taking this medicine include diarrhea, gas, headache, indigestion, nausea, stomach upset, temporary metallic taste, or vomiting. If they continue or are bothersome, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience chest pain or discomfort; dizziness or lightheadedness; fast or difficult breathing; fever, chills, or persistent sore throat; feeling of being unusually cold; general feeling of being unwell; muscle pain or weakness; slow or irregular heartbeat; unusual or persistent stomach pain or discomfort; unusual drowsiness; unusual tiredness or weakness. An allergic reaction to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, severe dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Overdose:IF OVERDOSE IS SUSPECTED, contact your local poison control center or emergency room immediately. Symptoms of overdose may include dizziness or light-headedness, fast or difficult breathing, feeling of being unusually cold, general feeling of being unwell, muscle pain or tenderness, slow or irregular heartbeat, unusual drowsiness, unusual stomach discomfort, or unusual weakness or tiredness.
Additional Information:This medicine is not a substitute for proper diet and regular exercise. It is recommended you attend a diabetes education program to better understand diabetes, prevention of complications, and all the important aspects of its treatment. These include meals/diet, exercise, weight loss, personal hygiene, medicine and blood glucose monitoring, and the need for regular eye, foot, and medical exams. Follow your doctor's instructions carefully. FOLLOW THE DIET AND EXERCISE PLAN provided by your doctor. Carry an identification card at all times that says you are diabetic. Monitor your blood sugar levels regularly according to your doctor's directions. If your blood sugar level is often higher or lower than it should be and you are taking this medicine according to directions, check with your doctor. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. KEEP THIS MEDICINE out of the reach of children and pets. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.
Copyright 2014 Wolters Kluwer Health, Inc.