Do not use if you are pregnant, nursing, or have been diagnosed with an inflammatory bowel disease or kidney condition. If you are taking any medications consult your healthcare professional before taking this or any other supplement. Do not exceed recommended daily intake. Stop taking this product 2 weeks prior to any surgery. Not intended for use by persons under 18. Keep out of the reach of children. Notice: This product contains senna and cascara sagrada. Read and follow directions carefully. Do not use if you have or develop diarrhea, loose stools, or abdominal pain because senna and cascara sagrada may worsen these conditions and by harmful to your health. Consult your physician if you have frequent diarrhea or if you are pregnant, nursing, taking medication, or have a medical condition.