Do not use this product if you are pregnant, breast-feeding, have kidney or gallbladder disorder or disease. This product is not recommended for prolonged use. This product is made with botanical herbs. When using this product you may experience nausea, dizziness, diarrhea or cramping. If you start to experience any of these symptoms, discontinue use of product immediately. If symptoms persist seek medical assistance. As with all herbal supplements, this product is not recommended for children without the supervision of a parent or guardian. This product contains Cascara Sagrada. Read and follow directions carefully. Do not use if you have or develop diarrhea, loose stools, or abdominal pain because Cascara Sagrada may worsen these conditions and be harmful to your health. Consult your physician, if you have frequent diarrhea or if you are pregnant, nursing, taking medication, or have a medical condition.