As with all creatine products, maintain an adequate state of hydration during use. Do not use if you suffer from diabetes of if you are prone to hyperglycemia or hypoglycemia. If you experience a skin rash or any other allergic reaction, discontinue use and consult a physician. Do not use if you have had a myocardial infraction (heart attack). Inhalation may amplify the inflammatory response in persons with asthma. Do not refrigerate. Processed in a facility that also process milk and soy ingredients. .