Rinsing your nasal passages with only plain water will result in a severe burning sensation. Use lukewarm water distilled, filtered or previously boiled water, properly mixed NeilMed® Sinus Rinse™ Packets. Do not rinse if nasal passages are completely blocked or if you have an ear infection or blocked ears. Please retain the enclosed brochure for instructions & other important information. Please keep out of reach of children. Store or keep in a cool & dry place. For ages 4 & up.