D-pol is intended only for healthy adults above the age of 18. Do not use if you are currently pregnant or nursing, could be pregnant or are attempting to become pregnant. All individuals should consult a licensed healthcare practitioner before using this product. Do not use this product if you have been diagnosed with or have a family history of (including, but not limited to): heart disease, thyroid disease, liver disease, cancer, Barrett's Esophagus, gasterophageal reflux, diabetes, hypoglycemia, hypo/hypertension, asthma, any psychiatric condition including depression or seizure disorder, or if you are using any other dietary supplement, prescription drug or over-the-counter drug intended to promote vasodilation, in particular those intended for erectile dysfunction. The combined use of vasodilatory supplements or drugs & D-pol could cause an unsafe drop in blood pressure. Discontinue use & contact a medical doctor immediately if you experience an irregular or rapid heart beat, chest pain, shortness of breath, dizziness, lightheadedness, fainting or presyncope, tremors, headache, nausea or other similar symptoms.