Take at bedtime only. Melatonin can induce drowsiness & sleep. Pregnant or nursing women, individuals taking sedatives or other medication(s), or persons who have a health condition should consult their physician before using this product. Do not use alcohol, drive a vehicle or operate machinery while taking this product. Do not use prior to surgery. Keep out of reach of children. For your protection, do not use if imprinted seal is broken or missing.