Consult a physician prior to use if you have a hormonal disorder, diabetes, liver or kidney disease, cerebral palsy, seizure disorders, migraine, depression and/or hypertension, or if you are taking blood pressure or sedative/hypnotic medications. Do not drive or use machinery for 5 hours after taking melatonin. If symptoms persist continuously for more than 4 weeks, or if pain or other factors appear to be the cause of sleeplessness, consult a physician. Do not use if you are taking immunosuppressive drugs and/or pregnant or breastfeeding. Keep out of reach of children.