Hepatitis A/Hepatitis B Combination Vaccine



Hepatitis A/Hepatitis B Combination Information

Hepatitis A is a liver disease that can cause stomach pain, diarrhea, loss of appetite, nausea, dark urine, yellow eyes or skin, and fever. Symptoms are more common in adults than they are in children. The disease is caused by the hepatitis A virus (HAV), which can be passed from person to person through contaminated food or water.

Although acute hepatitis A usually resolves itself within six months, the disease accounts for approximately 100 deaths per year in the United States.

Hepatitis B is a serious liver disease that can cause tiredness, dark urine, yellow eyes or skin (known as jaundice), and an enlarged liver. The virus is caused by Hepatitis B virus (HBV) and is spread primarily through contact with blood or bodily fluid of an infected person. Some of the ways people become infected are through the use of contaminated needles, unprotected sex, and contact with an infected mother during childbirth. Long-term infection of Hepatitis B can result in liver damage, liver cancer, cirrhosis (liver failure) or death.

Hepatitis A and Hepatitis B Vaccine Information

Hepatitis A vaccine is available as an individual vaccine or in combination with Hepatitis B vaccine.

Hepatitis A vaccine is given as an injection into the arm or thigh muscle, which is known as an intramuscular (IM) injection.

Hepatitis B vaccine is available as an individual vaccine or in combination with other vaccines, such as hepatitis A vaccine , H. influenzae type b (Hib) vaccine, or diphtheria/pertussis/tetanus and polio vaccines.

Hepatitis B vaccine is given as an injection into the arm or thigh muscle, which is known as an intramuscular (IM) injection.

For more information on Hepatitis A, visit our web page.
For more information on Hepatitis B, visit our web page.

Who Should Receive the Hepatitis A Vaccine?

  • All children between 12 months and 23 months old
  • People who live in a community with high rates of hepatitis A
  • People traveling to countries where hepatitis A is common
  • Men who have sex with men
  • People who inject illegal drugs
  • People with chronic liver disease
  • People who receive blood products to help their blood clot
  • People who work with HAV-infected animals or work with HAV in research settings

Who Should Receive the Hepatitis B Vaccine?

  • Everyone 18 years of age and younger
  • People with multiple sex partners
  • Anyone whose sex partner is infected with HBV
  • Men who have sex with men
  • People who inject illegal drugs
  • People with chronic liver or kidney disease
  • Hemodialysis patients
  • Healthcare workers or household contacts who might be exposed to an infected person's blood or bodily fluids
  • People who have HIV/AIDS
  • Those traveling to countries where Hepatitis B (Hep B) is common
  • People who have diabetes

Combination Hepatitis A/Hepatitis B Vaccination Schedule

  • Three doses: First dose, followed by a second dose 1 month after the first dose, followed by a third dose 6 months after the first dose

Side Effects

Mild-to-Moderate Problems

  • Soreness, redness, or swelling where the shot was given
  • Headache, tiredness, and loss of appetite

Severe Problems (Rare)

  • Difficulty breathing
  • Wheezing
  • Hives
  • Pale skin
  • Fast heartbeat
  • Dizziness

Who Should Not Receive the Hepatitis A Vaccine?

  • Those with moderate or severe illness (for example, a severe cold, flu or infection of the sinuses or lungs) should not receive the vaccine until symptoms of the illness improve.
  • Women who are pregnant or plan to become pregnant should ask their doctor if they should receive the vaccine.
  • Those who previously had a severe, life-threatening allergic reaction to the vaccine or any ingredient in the vaccine should not be vaccinated.

Who Should Not Receive the Hepatitis B Vaccine?

  • Those with moderate or severe illness (for example, a severe cold, flu or infection of the sinuses or lungs) should not receive the vaccine until symptoms of the illness improve.
  • Women who are pregnant or plan to become pregnant should ask their doctor if they should receive the vaccine.
  • Those who previously had a severe, life-threatening allergic reaction to the vaccine or any ingredient in the vaccine should not be vaccinated.

Additional Information

Tell your doctor or a healthcare provider if the person getting the vaccine has any severe allergies.

Call the Centers for Disease Control and Prevention (CDC) at 800-232-4636 or visit the CDC website, at  cdc.gov/vaccines, for more vaccine information.

This publication should be used for general educational purposes only and is not intended to be a substitute for professional medical advice. Be sure to contact your doctor, pharmacist, or other healthcare provider for more information about human papillomavirus. Although it is intended to be accurate, neither Walgreen Co., its subsidiaries or affiliates, nor any other party assumes liability for loss or damage due to reliance on this publication.

References

Atkinson W, Hamborsky J, McIntyre L, Wolfe S, eds. Centers for Disease Control and Prevention (CDC). Epidemiology and Prevention of Vaccine-Preventable Diseases. 10th ed. Washington, DC: Public Health Foundation, 2007.

Vaccine Information Statement: hepatitis A vaccine. Centers for Disease Control and Prevention (CDC). March 21, 2006.cdc.gov/vaccines/pubs/vis/default.htm. Accessed April 2008.

Vaccine Information Statement: Hepatitis B (Hep B) vaccine. Centers for Disease Control and Prevention (CDC). March 21, 2006.cdc.gov/vaccines/pubs/vis/default.htm. Accessed April 2008.


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