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Are there any prescription treatments for oral or vaginal yeast infections?


There are prescription treatments for a yeast infection, both vaginal and in the mouth. Prescription medicines can be used to treat yeast infections in the mouth - an option that is not available in over-the-counter or alternative forms. Prescription medicines are also available for vaginal infections that are not cured by over-the-counter products. In both cases, prescription medicines can be applied to the affected areas or taken as oral tablets.


Nystatin (Mycostatin®) is a medicine that is applied to the mouth or vagina to treat yeast infections. For mouth infections, it's available in liquid and tablet forms. For vaginal infections, it's available as a tablet insert. The oral medication is usually taken four to five times daily, while vaginal tablets are used just once daily.

Fluconazole and ketoconazole

Fluconazole (Diflucan®) and ketoconazole (Nizoral®) are oral antifungal medications that are very effective in treating yeast infections of the vagina and mouth. Vaginal yeast infections can be treated with a single oral dose, while mouth infections may require daily oral doses for up to two weeks, depending on how severe the infection is.

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Answers to questions regarding information about medications or health conditions are not for diagnostic or treatment purposes and are not conclusive as to the presence or absence of any health condition. Consult your physician for diagnosis and treatment of your medical condition. The information provided is not a substitute for medical advice. Advances in medicine may cause this information to become outdated, invalid or subject to debate. Professional opinions and interpretations of the scientific literature may vary. Walgreens' terms of use and general warranty disclaimer apply to all services provided. If you are in need of immediate medical attention, contact your physician, poison control center or emergency medical professional. If you need to speak with a pharmacist for non-emergency matters, contact your local Walgreens pharmacist or call a pharmacist toll-free at 1 (877) 250-5823.

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