What are H2 blockers?
H2-receptor blockers are a group of medications that prevent the release of stomach acid and
are used to treat heartburn and ulcer. They include Tagamet®, (cimetidine), Zantac®
(famotidine) and Axid® (nizatidine). These drugs are available over the counter in low doses to treat
minor heartburn. They're prescribed in higher doses to treat a more severe type of heartburn
called reflux disease (also called gastroesophageal reflux disease, or GERD), stomach ulcers,
and intestinal ulcers. People tolerate these medicines well, reporting few side effects. The
most commonly reported side effects include mild drowsiness, confusion, rash, fatigue,
headache, diarrhea, and constipation. Be sure to talk with your doctor if you experience any
unusual or more severe reactions to these medications.
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