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What are the side effects of tamoxifen?


Tamoxifen (Nolvadex®) is a medicine used to treat estrogen-sensitive breast cancer. Most side effects of tamoxifen are mild and don't require stopping the drug as a cancer treatment. The drug works by blocking the effects of estrogen in the breast tissue and slowing tumor growth.

Most common tamoxifen side effects

Tamoxifen's most prevalent side effects include hot flashes, vaginal discharge, abnormal vaginal bleeding, and weight gain. Other, less common side effects include headache, nausea or vomiting, and skin rash. Some serious, but rare side effects include an increased risk of blood clots, cancer of the uterus, more severe cataracts, and temporary liver damage, resulting in yellowing of the eyes or skin. You shouldn't take tamoxifen if you have a history of blood clots.

Get information on breast cancer with an article in our Health Encyclopedia.

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