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What are the side effects of Synvisc?


Synvisc® (hylan G-F 20) is an injectable drug used to treat people with osteoarthritis of the knee. It thickens the fluid inside the joint to its natural shock-absorbing consistency. This helps to prevent pain and stiffness in the joint. Doctors prescribe it when nondrug treatments, nonprescription drugs, and other prescription drugs don't work. The most commonly reported side effects of Synvisc® are mild pain or swelling caused by the injection. These effects usually go away within three days after the injection. To lessen side effects, don't do any strenuous or weight-bearing exercises immediately after receiving your shot. Allergic reactions or damage to the joint occur rarely. Also, there are a few reported cases of gout in the knee occurring after an injection of Synvisc®. If you have allergies to feathers, eggs, or other bird products, you should tell your doctor before using Synvisc®. Promptly report any symptoms of an allergic reaction to your doctor. Such symptoms might include a rash, itching, or trouble breathing. People with infections in their joints should not get Synvisc® injections.

Read more about osteoarthritis in our Health Encyclopedia.

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