Vicodin Dosing Information

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How should I take Vicodin?


You should take Vicodin (hydrocodone/APAP) exactly as directed by your doctor. Typically, this will be one or two doses every four to six hours. Always take Vicodin with food to minimize digestive distress. Never abruptly stop taking Vicodin, as this can cause withdrawal symptoms.

What should I avoid while taking Vicodin?

Because the medication causes drowsiness, you should never operate machinery or drive a motor vehicle while taking Vicodin (hydrocortisone/APAP). Avoid taking other medications that contain acetaminophen, as this can cause liver damage. Avoid additional medications that contain narcotic agents as this could lead to overdose. Avoid alcohol while taking Vicodin, as this can increase the effects of the narcotic and cause serious adverse reactions.

What happens if I miss a dose of Vicodin?

Since Vicodin (hydrocodone-APAP) is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.

Can I take too much Vicodin?

Yes. Vicodin (hydrocodone-APAP) is a strong combination of medicines and should only be used for the condition for which it was prescribed. An overdose can occur with this medication if prescribed doses are not followed. Contact your doctor immediately if any symptoms of overdose appear. They include: bloody or cloudy urine; lapsing of consciousness; chest pain or discomfort; cold and clammy skin; decreased awareness or responsiveness; general discomfort or feeling of illness; increased sweating; slow or irregular heartbeat; lightheadedness; dizziness or fainting; sudden decrease in urine output; unpleasant breath odor; or vomiting blood.

If you or someone you know has concerns or questions about dosage measurements, talk with your doctor or pharmacist.

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