Skip main navigation
Walgreens Walgreens Logo
Logo Walgreens Logo
start main content

Claritin and Allegra Differences



How do Claritin-D and Claritin, and Allegra-D and Allegra differ from each other?


The biggest difference between Claritin-DŽ and ClaritinŽ (loratadine) is that ClaritinŽ is only an antihistamine. Claritin-DŽ is both a decongestant and an antihistamine (pseudoephedrine). Allegra-DŽ and AllegraŽ (fexofenadine) have the same difference as ClaritinŽ and Claritin-DŽ. Allegra-DŽ and Claritin-DŽ should be used when allergy symptoms include a stuffy nose because decongestants help dry out nasal congestion. All of these products are typically free of side effects, but the decongestant pseudoephedrine can result in insomnia. If you have high blood pressure, an overactive thyroid or an enlarged prostate consult your doctor before taking pseudoephedrine-containing medicines like Claritin-DŽ and Allegra-DŽ.

ClaritinŽ and AllegraŽ are available over-the-counter. Claritin-DŽ and Allegra-DŽ are available behind-the-counter because they contain pseudoephedrine. Check with a pharmacist or physician before using any new medication or drug.

Back to Ask a Pharmacist


Answers to questions regarding information about medications or health conditions are not for diagnostic or treatment purposes and are not conclusive as to the presence or absence of any health condition. Consult your physician for diagnosis and treatment of your medical condition. The information provided is not a substitute for medical advice. Advances in medicine may cause this information to become outdated, invalid or subject to debate. Professional opinions and interpretations of the scientific literature may vary. Walgreens' terms of use and general warranty disclaimer apply to all services provided. If you are in need of immediate medical attention, contact your physician, poison control center or emergency medical professional. If you need to speak with a pharmacist for non-emergency matters, contact your local Walgreens pharmacist or call a pharmacist toll-free at 1 (877) 250-5823.

Your Digital Health Advisor. Powered by WebMD. Manage diabetes with this easy online tool.* Get started.
Your Digital Health Advisor. Powered by WebMD. Manage diabetes with this easy online tool.* Get started.

BalanceŽ Rewards for Healthy Choices

20 Points
20 Points

Now you can track your blood pressure and blood glucose.

Start earning points Go Arrow