The FDA has approved one, and only one. alli is the only over-the-counter weight loss aid with FDA approval.
Learn how alli works now.
FREE personalized online support plan. Learn more.

alli is used by millions to lose weight safely. It works in your digestive tract and doesn't affect your head or heart. It simply blocks about 25% of the fat you eat, without being a stimulant or appetite suppressant. So, when you lose 2 pounds, alli can help you lose 1 more.* Plus, alli's free personalized online support plan offers scientifically proven tools to help achieve and maintain a healthier weight.

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How alli works. Learn more.
Myalliplan. Learn more,
How alli works

How can you be sure that the hard work you put into losing weight pays off? For every 2 pounds you lose through healthy eating and exercise, alli can help you lose 1 more.* Together with myalliplan, you'll have the support you need to achieve a healthier weight.

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Myalliplan is a personalized program designed to help you lose weight long-term. Follow 26 weekly steps on topics like portions, shopping and staying motivated. Plus, get tools like a weekly Check-in Wizard, Visual Progress Tracker, Meal and Activity Planners and a community of support.

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Shop all.


alli starter pack. Shop.

alli starter pack
Get everything you need
to get started: alli weight
loss capsules, carrying case,
online program guide,
reference booklets
and more.

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alli refill pack. Shop.

alli refill pack
If you've already started
the alli program, it's easy to
get the refill capsules you
need when you need them.

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More tools from alli.
Put a spring in your step. Learn more.
Healthy spring eating. Learn more.
Put a spring in your step

Being physically active is essential to living a healthier life. Physical activity helps keep us mentally focused, energized and positive. Try these simple ideas today.

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Healthy spring eating

A healthy, low-fat diet doesn't have to be a sacrifice. Plus, you can still enjoy the foods you love. Try these fresh tips to cut the fat but keep the delicious taste.

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*alli plus a reduced-calorie low-fat diet. alli (Orlistat 60mg) is for overweight adults. Use as directed.