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Typhoid vaccine

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Vaccines offered at Walgreens vary by state, age and health conditions. Talk to your local pharmacist about availability.
Quick facts
Recommended for
Travelers and specific groups
Frequency
Capsule: 1 capsule every other day for 4 days at least 1 week prior to travel

Injection: 1 dose at least 2 weeks prior to travel

What is typhoid?

Typhoid is a serious bacterial illness that can cause a high fever accompanied by weakness, stomach pains, headache, loss of appetite and sometimes rash. If untreated, up to 30 percent of typhoid cases are fatal. The disease is spread mainly through contaminated food or water but it’s also possible to get typhoid from close contact with an infected person.

Incidents of typhoid are very rare in the U.S. and most reported cases of typhoid infections are brought back by travelers. The risk of typhoid infection is greatest for travelers to South Asia, Africa, the Caribbean and Central and South America.

Frequently Asked Questions

  • Getting a typhoid vaccine can prevent typhoid infection. Since none of the available typhoid vaccines are 100 percent effective, travelers should still take precautions to avoid ingestion of contaminated food and water.

    There are two typhoid vaccines available in the U.S.: injection and oral capsule, which are recommended based on age and departure timeline.

    To learn more about the typhoid vaccine from the CDC, download this PDFto learn more about the typhoid vaccine from CDC. Opens in new tab or visit the CDC websiteOpens in new tab.

    • People traveling to parts of the world where typhoid is prevalent
    • Travelers ages 2+ should receive the injection at least 2 weeks prior to expected exposure
    • Travelers ages 6+ are approved to take the capsule at least 1 week prior to travel
    • People in close contact with others who are infected with typhoid

    People who are pregnant or plan to become pregnant should ask their doctor if they should receive the vaccine.

    • People who previously had a severe, life-threatening allergic reaction to the vaccine or any ingredient in the vaccine
    • People should not receive the oral vaccine if they have a weakened immune system for any reason, including:
      • HIV/AIDS or another disease that affects the immune system
      • Treatment with steroids, such as prednisone, for 2 weeks or longer
      • People with cancer or undergoing cancer treatment
    • People on antibiotics who plan to receive the oral typhoid vaccine should wait until 3 days after finishing the antibiotic regimen

  • Mild-to-moderate side effects:

    • Abdominal pain, nausea, vomiting, diarrhea, headache
    • Injection
      • Soreness, redness, or swelling at the injection site
      • Headache
      • Flu-like symptoms
    • Oral capsule
      • Fever
      • Skin rash

    Severe side effects, although rare, may include serious allergic reactions. Symptoms include:

    • Difficulty breathing
    • Wheezing
    • Hives
    • Pale skin
    • Fast heartbeat
    • Dizziness

    Over-the-counter pain relievers such as acetaminophen or ibuprofen can help ease pain and reduce fever. Contact your doctor or pharmacist if you have any unexpected or worsening reactions after receiving a vaccine.

If you believe you have a medical emergency, please call 911.

References:

Centers for Disease Control and Prevention. CDC Yellow Book 2020: Health Information for International Travel. New York: Oxford University Press; 2017.

Vaccine Information Statement: Typhoid Vaccines (What You Need to Know). Centers for Disease Control and Prevention (CDC).10/30/2019. https://www.cdc.gov/vaccines/hcp/vis/vis-statements/typhoid.pdf. Accessed September 2021.

This publication should be used for general educational purposes only and is not intended to be a substitute for professional medical advice. Although it is intended to be accurate, neither Walgreen Co., its subsidiaries or affiliates, nor any other party assumes liability for loss or damage due to reliance on this publication.