Prescription Cold Sore Treatment Online

Treat cold sores by getting Valacyclovir, an antiviral medication, prescribed online through Walgreens Virtual Healthcare.

Valacyclovir (Valtrex) for Cold Sore Treatment

  • Valacyclovir (brand name Valtrex) is an oral antiviral medication often prescribed to treat infections caused by the herpes virus, including cold sores (oral herpes).

    While valacyclovir does not cure the infection, it can help reduce outbreaks, improve symptoms like tingling, burning, pain and itching, and speed up healing—making outbreaks less severe.

    Valacyclovir works by blocking the herpes virus from making more copies of itself. This medication works best when it is started as soon as possible at the earliest symptoms of a cold sore, ideally before a blister develops.

  • Cold sores generally take a few weeks to heal on their own. However, valacyclovir can begin to help your symptoms and decrease the duration of the outbreak soon after you take it. It’s very important to take the medicine exactly the way your healthcare provider tells you, to make sure the outbreak is fully suppressed.

  • Valacyclovir can be used to treat cold sores in individuals that are 12 years of age or older.

    Your healthcare provider will determine whether this medication is appropriate for you. Be sure to inform your provider about all medications, supplements, and any health conditions you have. This helps them develop a safe and effective treatment plan and assess potential interactions with other medications.

  • As with any medication, you may experience side effects while taking valacyclovir. The most common side effects include headaches, nausea, and stomach pain. Thrombotic Thrombocytopenic Purpura (TTP) and Hemolytic Uremic Syndrome (HUS) may occur in people with weakened immune systems causing small clots to form throughout the body and decreasing blood flow to areas of the body such as the brain, heart and kidney. Other serious side effects include kidney failure and nervous system problems, such as aggressive behavior, unsteady or shaky movement, confusion, speech problems, hallucinations, seizures, or coma. Contact your healthcare provider right away if you experience any symptoms of nervous system problems. Seek immediate medical attention if you notice any signs of a serious allergic reaction, including swelling in your face, lips, tongue or throat, severe rash or itching, very fast heartbeat, trouble breathing or swallowing, fainting or feeling dizzy.

  • The Walgreens Virtual Cold SoreOpens in a new tab visit makes it simple and convenient to get care. During your visit, you’ll begin by completing a questionnaire about your medical history and current symptoms, as well as upload a photo of your oral cold sore outbreak. A provider will review your responses and photo and may prescribe medication if appropriate.

  • There are other prescription antiviral medications to treat cold sores. Some of these medications are taken by mouth while others are applied directly on the cold sore. Your healthcare provider can decide which treatment option is right for you.

Frequently Asked Questions

  • Cold sores are commonly caused by the herpes simplex virus type 1 (HSV‑1). Many people are exposed to this virus in childhood or young adulthood, often from something as simple as sharing a drink, kissing a family member, or using the same utensils as someone who has the virus. Once a person becomes infected, the virus stays in the body for life. Some people with HSV-1 rarely get cold sores, while others may get them often.

  • Cold sores usually go away on their own within a few weeks. Prescription antiviral medications can help cold sores heal more quickly. They can also be used to decrease the number of recurrences in people who frequently get them.

  • While cold sores may go away on their own, if they are painful or bothersome getting treatment right away can help. Prescription antiviral medications work best when started as soon as symptoms appear. It is recommended that you see a healthcare provider if you have:

    • Eczema
    • Multiple cold sores, cold sores near the eye, or severe pain
    • Cold sores lasting more than 2 weeks
    • Six or more occurrences per year
    • Are taking immune-suppressing medication (e.g., post-transplant, severe psoriasis)
    • An immune-weakening condition (e.g., cancer, HIV)
    • Recently been on an immune-suppressing treatment (e.g., chemotherapy, bone marrow transplant)
  • Even when taking a prescription antiviral medication such as valacyclovir to treat cold sores, the virus can still spread to others. A person is considered contagious until all the sores have scabbed over.

  • HSV-1, the virus that usually causes cold sores, is not typically classified as a sexually transmitted infection (STI). While the virus can spread through close personal contact, most people are infected through nonsexual contact with the saliva of someone who already has HSV-1.

    HSV-1 is different from the herpes simplex virus type 2 (HSV-2), which causes most cases of genital herpes. Genital herpes is a STI.

  • Valacyclovir (Valtrex)

    Contraindications

    • Hypersensitivity to valacyclovir (e.g., anaphylaxis), acyclovir, or any of its components.

    Warnings and Precautions

    • Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS) has occurred in people with advanced HIV-1 disease and also in allogeneic bone marrow transplant and renal transplants recipients receiving 8 grams per day of valacyclovir in clinical trials. Treatment should be discontinued if clinical signs, symptoms, and laboratory abnormalities consistent with TTP/HUS occur.
    • Acute renal (kidney) failure may occur in elderly individuals (with or without reduced kidney function), those with kidney disease receiving more than the recommended dose of valacyclovir for their level of kidney function, individuals who are also taking medications that may be harmful to the kidneys, or who are not adequately hydrated. Valacyclovir should be used with caution in the elderly, and the dose should be reduced in patients with reduced kidney function.
    • Serious central nervous system effects like agitation, hallucinations, confusion, delirium, seizures, and a condition of the brain may occur in adult and pediatric individuals (with or without decreased kidney function), and in those with kidney disease who are receiving more than the recommended dose of valacyclovir for their level of kidney function. These adverse effects are more likely to occur in the elderly. Stop taking valacyclovir and call your doctor right away if you notice these symptoms.
    • Speak with your healthcare provider if you are pregnant or plan to become pregnant. It is not known if valacyclovir will harm your unborn baby.
    • Speak with your healthcare provider if you are breastfeeding or plan to breastfeed. Valacyclovir may pass into your breast milk.

    Common Side Effects

    • Headache, nausea, and abdominal pain.

    Significant Interactions

    • There are no known serious interactions between valacyclovir and other medicines or foods. However, you should still check with your doctor or pharmacist before starting any new medication.

References

Disclaimers

*Currently available in the following states: AL, AZ, CA, CO, CT, FL, GA, IL, IN, KY, LA, MA, MD, MI, MN, MO, NC, NJ, NV, NY, OH, OK, PA, SC, TN, TX, VA, WA, WI

Based on national averages. Actual times may vary.

Labcorp and Quest staff are not associates, employees and/or agents of Walgreen Co. or any Walgreens subsidiary or affiliated company. Lab service will be a separate fee, price may vary.

Prescription based on medical evaluation and not guaranteed.

Walgreens-affiliated medical practices are independently owned and operated by licensed physicians who provide services using the Walgreens virtual care program telehealth platform. For more information about the relationship between Walgreens and the medical practices click here Opens in a new window.

Walgreens Health Medical Group California P.C. is a California professional medical corporation utilizing the fictitious name “Walgreens Health Medical Group California P.C.” pursuant to Cal. Bus. & Prof. Code § 2415. To view the Fictitious Name Permit click here Opens in a new window.