About Naloxone


No Rx Required

Naloxone (brand name Narcan®) is an opioid antidote that can reverse an overdose. It's now available without a prescription at select Walgreens pharmacies across the U.S.

Naloxone saves lives. If you or a loved one shows signs of opioid addiction or regularly takes prescribed opioids, talk to your pharmacist about keeping naloxone handy.

How to use naloxone

Naloxone comes in two forms: nasal spray and injection. Both take 3-5 minutes to work and last 30-90 minutes. Your pharmacist can teach you how to use naloxone.

Naloxone isn't a substitute for medical care. Call 911 and seek help immediately if someone shows symptoms of an overdose, including:

  • Labored breathing, struggling for breath, snoring or gurgling sounds
  • Bluish lips and/or fingertips
  • Pale, clammy skin
  • Awake but unable to talk or respond
  • Small pupils
  • Limp body

Find naloxone near you

Find prescription and non-prescription naloxone at any of the 8,000+ Walgreens pharmacies nationwide.

What to expect when purchasing naloxone

How to administer naloxone

Step-by-step instructions you need to know

Read our guide ›

FAQ about naloxone

How does naloxone work?

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Naloxone counteracts life-threatening depression of the central nervous and respiratory systems, allowing overdose victims to breathe normally.

It usually takes about 3–5 minutes for naloxone to work, and the effects last 30–90 minutes.

Is it dangerous to administer naloxone to a person who is not overdosing?

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No, there is no effect if opioids are not present. Naloxone will not counteract overdoses for other substances such as alcohol, benzodiazepines or sleeping pills.

Where is naloxone currently available at Walgreens pharmacies?

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Naloxone is currently available without a prescription in Walgreens pharmacies across 44 states and Washington D. C., including:

Alabama, Alaska, Arizona, Arkansas, California, Colorado, Connecticut, District of Columbia, Florida, Georgia, Idaho, Illinois, Indiana, Iowa, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Minnesota, Mississippi, Missouri, Montana, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Carolina, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, South Dakota, Tennessee, Texas, Utah, Vermont, Virginia, Washington, West Virginia, Wisconsin.

Prescription naloxone is available in all Walgreens pharmacies.

When will non-prescription naloxone be available in all states?

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State rules and regulations determine how naloxone may be dispensed. We'll continue to work with regulators in the remaining states to help customers access naloxone.

How are you able to make naloxone available without a prescription?

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State rules and regulations determine how naloxone may be dispensed. Most states that allow naloxone to be dispensed without a prescription require the pharmacy to obtain a standing order from a physician.

Will naloxone be available OTC?

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Even if the naloxone is available without a prescription, it is only available at the pharmacy and a pharmacist must give medication instructions.

Is naloxone covered by insurance? What's the cost of naloxone?

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Most insurance plans cover naloxone. For medication price and coverage information, contact your local pharmacy.